Applications of chitosan-based biomaterials: From preparation to spinal cord injury neuroprosthetic treatment

W Xiang, H Cao, H Tao, L Jin, Y Luo, F Tao… - International Journal of …, 2023 - Elsevier
Spinal cord injury (SCI)-related disabilities are a serious problem in the modern society.
Further, the treatment of SCI is highly challenging and is urgently required in clinical …

Molecular mechanisms and clinical application of multipotent stem cells for spinal cord injury

M Szymoniuk, J Litak, L Sakwa, A Dryla, W Zezuliński… - Cells, 2022 - mdpi.com
Spinal Cord Injury (SCI) is a common neurological disorder with devastating psychical and
psychosocial sequelae. The majority of patients after SCI suffer from permanent disability …

Therapeutic strategy of mesenchymal-stem-cell-derived extracellular vesicles as regenerative medicine

Y Matsuzaka, R Yashiro - International Journal of Molecular Sciences, 2022 - mdpi.com
Extracellular vesicles (EVs) are lipid bilayer membrane particles that play critical roles in
intracellular communication through EV-encapsulated informative content, including …

Stem cell therapies for neurological disorders: current progress, challenges, and future perspectives

R Rahimi Darehbagh, SA Seyedoshohadaei… - European Journal of …, 2024 - Springer
Stem cell-based therapies have emerged as a promising approach for treating various
neurological disorders by harnessing the regenerative potential of stem cells to restore …

Study of nerve cell regeneration on nanofibers containing cerium oxide nanoparticles in a spinal cord injury model in rats

B Rahimi, Z Behroozi, A Motamednezhad… - Journal of Materials …, 2023 - Springer
Since the CNS is unable to repair itself via neuronal regeneration in adult mammals,
alternative therapies need to be found. The use of cerium oxide nanoparticles to repair …

Application and prospects of somatic cell reprogramming technology for spinal cord injury treatment

R Yang, J Pan, Y Wang, P Xia, M Tai… - Frontiers in Cellular …, 2022 - frontiersin.org
Spinal cord injury (SCI) is a serious neurological trauma that is challenging to treat. After
SCI, many neurons in the injured area die due to necrosis or apoptosis, and astrocytes …

[HTML][HTML] Efficacy of mesenchymal stromal cells intraspinal transplantation for patients with different degrees of spinal cord injury: A systematic review and meta …

C Mou, X Wang, W Li, Z Li, N Liu, Y Xu - Cytotherapy, 2023 - Elsevier
Background aims Several studies have reported that mesenchymal stromal cells (MSCs)
may improve neurological functions in patients with spinal cord injury (SCI). In this study, we …

[HTML][HTML] Medical Ozone as a Therapeutic Option in Musculoskeletal Pain Control: A Critical Review of Clinical Trials Considering Safety and Quality Indicators for …

LT de Araújo, PC da Silva… - The Yale Journal of …, 2024 - pmc.ncbi.nlm.nih.gov
Background: Drug therapies have been widely applied for pain management, however,
there are important side effects such as those related to corticosteroids and opioids. Recent …

Autophagy regulation combined with stem cell therapy for treatment of spinal cord injury

Y Shen, YP Wang, X Cheng, X Yang… - Neural Regeneration …, 2023 - journals.lww.com
Stem cells are a group of cells with unique self-renewal and differentiation abilities that have
great prospects in the repair of spinal cord injury. However, stem cell renewal and …

Transplantation of autologous mesenchymal stromal cells in complete cervical spinal cord injury: a pilot study

CT Macêdo, BS de Freitas Souza, CF Villarreal… - Frontiers in …, 2024 - frontiersin.org
Objective Spinal cord injury (SCI) is a serious condition that can lead to partial or complete
paraplegia or tetraplegia. Currently, there are few therapeutic options for these conditions …