Chemical strategies to engineer hydrogels for cell culture

J Lou, DJ Mooney - Nature Reviews Chemistry, 2022 - nature.com
Two-dimensional and three-dimensional cell culture systems are widely used for biological
studies, and are the basis of the organoid, tissue engineering and organ-on-chip research …

Soft materials by design: unconventional polymer networks give extreme properties

X Zhao, X Chen, H Yuk, S Lin, X Liu… - Chemical Reviews, 2021 - ACS Publications
Hydrogels are polymer networks infiltrated with water. Many biological hydrogels in animal
bodies such as muscles, heart valves, cartilages, and tendons possess extreme mechanical …

Ultrasound-based micro-/nanosystems for biomedical applications

H Huang, Y Zheng, M Chang, J Song, L Xia… - Chemical …, 2024 - ACS Publications
Due to the intrinsic non-invasive nature, cost-effectiveness, high safety, and real-time
capabilities, besides diagnostic imaging, ultrasound as a typical mechanical wave has been …

Chemically modified and conjugated antimicrobial peptides against superbugs

W Li, F Separovic, NM O'Brien-Simpson… - Chemical Society …, 2021 - pubs.rsc.org
Antimicrobial resistance (AMR) is one of the greatest threats to human health that, by 2050,
will lead to more deaths from bacterial infections than cancer. New antimicrobial agents …

Multivascular networks and functional intravascular topologies within biocompatible hydrogels

B Grigoryan, SJ Paulsen, DC Corbett, DW Sazer… - Science, 2019 - science.org
Solid organs transport fluids through distinct vascular networks that are biophysically and
biochemically entangled, creating complex three-dimensional (3D) transport regimes that …

Collagen-and hyaluronic acid-based hydrogels and their biomedical applications

Q Xu, JE Torres, M Hakim, PM Babiak, P Pal… - Materials Science and …, 2021 - Elsevier
Hydrogels have been widely investigated in biomedical fields due to their similar physical
and biochemical properties to the extracellular matrix (ECM). Collagen and hyaluronic acid …

Hydrogel-based 3D bioprinting: A comprehensive review on cell-laden hydrogels, bioink formulations, and future perspectives

JM Unagolla, AC Jayasuriya - Applied materials today, 2020 - Elsevier
Hydrogel plays a vital role in cell-laden three dimensional (3D) bioprinting, whereas those
hydrogels mimic the physical and biochemical characteristics of native extracellular matrix …

Progress and potential in organoid research

G Rossi, A Manfrin, MP Lutolf - Nature Reviews Genetics, 2018 - nature.com
Tissue and organ biology are very challenging to study in mammals, and progress can be
hindered, particularly in humans, by sample accessibility and ethical concerns. However …

Hydrogel scaffolds for tissue engineering: the importance of polymer choice

CD Spicer - Polymer Chemistry, 2020 - pubs.rsc.org
Hydrogel scaffolds that can repair or regrow damaged biological tissue have great potential
for the treatment of injury and disease. These biomaterials are widely used in the tissue …

Design and applications of photoresponsive hydrogels

L Li, JM Scheiger, PA Levkin - Advanced Materials, 2019 - Wiley Online Library
Hydrogels are the most relevant biochemical scaffold due to their tunable properties,
inherent biocompatibility, and similarity with tissue and cell environments. Over the past …