Single-and multifraction stereotactic radiosurgery dose/volume tolerances of the brain

MT Milano, J Grimm, A Niemierko, SG Soltys… - International Journal of …, 2021 - Elsevier
Purpose As part of the American Association of Physicists in Medicine Working Group on
Stereotactic Body Radiotherapy investigating normal tissue complication probability (NTCP) …

Radiation therapy for extensive-stage small-cell lung cancer in the era of immunotherapy

Y Tian, J Ma, X Jing, X Zhai, Y Li, Z Guo, J Yu, H Zhu - Cancer Letters, 2022 - Elsevier
Unlike non-small-cell lung cancer (NSCLC), the progression of small-cell lung cancer
(SCLC) is slow. Extensive-stage SCLC (ES-SCLC) is a serious threat to human health, with …

Single-cell sequencing reveals the landscape of the human brain metastatic microenvironment

Q Song, J Ruiz, F Xing, HW Lo, L Craddock… - Communications …, 2023 - nature.com
Brain metastases is the most common intracranial tumor and account for approximately 20%
of all systematic cancer cases. It is a leading cause of death in advanced-stage cancer …

Dose-response effect and dose-toxicity in stereotactic radiotherapy for brain metastases: a review

M Loo, JB Clavier, J Attal Khalifa, E Moyal, J Khalifa - Cancers, 2021 - mdpi.com
Simple Summary Brain metastases are one of the most frequent complications for cancer
patients. Stereotactic radiosurgery is considered a cornerstone treatment for patients with …

Harnessing immunotherapy for brain metastases: insights into tumor–brain microenvironment interactions and emerging treatment modalities

D Zhou, Z Gong, D Wu, C Ma, L Hou, X Niu… - Journal of Hematology & …, 2023 - Springer
Brain metastases signify a deleterious milestone in the progression of several advanced
cancers, predominantly originating from lung, breast and melanoma malignancies, with a …

Local control outcomes for combination of stereotactic radiosurgery and immunotherapy for non-small cell lung cancer brain metastases

M Abdulhaleem, H Johnston, R D'Agostino Jr… - Journal of Neuro …, 2022 - Springer
Background Previous series have demonstrated CNS activity for immune checkpoint
inhibitors, yet no prior data exists regarding whether this activity can improve outcomes of …

Risk factors for progression and toxic effects after preoperative stereotactic radiosurgery for patients with resected brain metastases

RS Prabhu, T Akinyelu, ZK Vaslow, JK Matsui… - JAMA …, 2023 - jamanetwork.com
Importance Preoperative stereotactic radiosurgery (SRS) has been demonstrated as a
feasible alternative to postoperative SRS for resectable brain metastases (BMs) with …

Immune checkpoint inhibition in patients treated with stereotactic radiation for brain metastases

ES Kowalski, JS Remick, K Sun, GS Alexander… - Radiation …, 2020 - Springer
Purpose Stereotactic radiation therapy (SRT) and immune checkpoint inhibitors (ICI) may act
synergistically to improve treatment outcomes but may also increase the risk of symptomatic …

Factors associated with radiation necrosis and intracranial control in patients treated with immune checkpoint inhibitors and stereotactic radiotherapy

J Hall, K Lui, X Tan, J Shumway, F Collichio… - Radiotherapy and …, 2023 - Elsevier
Abstract Background and Purpose Emerging data suggest immune checkpoint inhibitors
(ICI) and stereotactic radiosurgery (SRS) or radiotherapy (SRT) may work synergistically …

Efficacy of laser interstitial thermal therapy for biopsy-proven radiation necrosis in radiographically recurrent brain metastases

M Chan, S Tatter, V Chiang, P Fecci… - Neuro-oncology …, 2023 - academic.oup.com
Background Laser interstitial thermal therapy (LITT) in the setting of post-SRS radiation
necrosis (RN) for patients with brain metastases has growing evidence for efficacy …