Adult neurogenesis in the mammalian brain is often viewed as a continuation of
neurogenesis at earlier, developmental stages. Here, we will critically review the extent to …

Highlights•Cortical interneurons originate in the embryonic subcortical
telencephalon.•Spatial and temporal control of progenitor differentiation generates …

Summary Histone H3. 3 glycine 34 to arginine/valine (G34R/V) mutations drive deadly
gliomas and show exquisite regional and temporal specificity, suggesting a developmental …

Cortical GABAergic inhibitory interneurons have crucial roles in the development and
function of the cerebral cortex. In rodents, nearly all neocortical interneurons are generated …

Intellectual disability (ID) and autism spectrum disorder (ASD) are the most common
neurodevelopmental disorders and are characterized by substantial impairment in …

Characterizing epigenetic heterogeneity at the cellular level is a critical problem in the
modern genomics era. Assays such as single cell ATAC-seq (scATAC-seq) offer an …

Promoting residential cells, particularly endogenous neural stem and progenitor cells
(NSPCs), for tissue regeneration represents a potential strategy for the treatment of spinal …

The development of three-dimensional culture methods has allowed for the study of
developing cortical morphology in human cells. This provides a new tool to study the …

The striatum is a central regulator of behavior and motor function through the actions of D1
and D2 medium-sized spiny neurons (MSNs), which arise from a common lateral ganglionic …

Neural stem cells (NSCs) reside in widespread regions along the lateral ventricle and
generate diverse olfactory bulb (OB) interneuron subtypes in the adult mouse brain …