Originally published in February 2004. This guideline is more than 5 years old and has not
yet been updated to ensure that it reflects current knowledge and practice. In accordance …

Cirrhosis is the end stage of many forms of liver pathologies including hepatitis. The liver is
known for its vital role in the processing of xenobiotics, including drugs and toxic …

Background: Over the past decade, use of the atypical antipsychotic drugs clozapine,
risperidone, olanzapine, and quetiapine has significantly changed the treatment of …

The need to develop new antipsychotics that have fewer motor adverse effects and offer
better treatment of negative symptoms has led to a new generation of drugs. Most of these …

Ziprasidone is a novel antipsychotic agent with a pharmacological profile distinct from that of
other currently available novel or classical antipsychotics. In preclinical studies, ziprasidone …

OBJECTIVE: Safe prescribing practices to minimize pharmaceutically induced liver damage
or worsening of preexisting conditions require knowledge about medicines with hepatotoxic …

Psychoses are major mental disorders marked by derangement of personality and loss of
contact with reality, and are common in the elderly. Various hypotheses suggest the pivotal …

Posttraumatic stress disorder (PTSD) has a considerable impact on a person's quality of life
and functioning, and there is some evidence that disturbed sleep is an important feature. 1 …

This paper reviews the clinical pharmacology, efficacy and safety of the new atypical
antipsychotic, ziprasidone. All published citations regarding ziprasidone were retrieved and …