Sterically demanding macrocyclic Eu (III) complexes for selective recognition of phosphate and real-time monitoring of enzymatically generated adenosine …
SE Bodman, C Breen, S Kirkland, S Wheeler… - Chemical …, 2022 - pubs.rsc.org
The design of molecular receptors that bind and sense anions in biologically relevant
aqueous solutions is a key challenge in supramolecular chemistry. The recognition of …
aqueous solutions is a key challenge in supramolecular chemistry. The recognition of …
Monitoring of phosphatase and kinase activity using 31 P NMR spectroscopy
X Guo, B Han, W Qiu, P Deng, S Fu, J Ying… - New Journal of …, 2023 - pubs.rsc.org
Traditionally, enzymatic assays require the addition of labels or exogenous supplementation
sources. Phosphorus-31 nuclear magnetic resonance (31P NMR) spectroscopy has proven …
sources. Phosphorus-31 nuclear magnetic resonance (31P NMR) spectroscopy has proven …
Direct monitoring of biocatalytic deacetylation of amino acid substrates by 1 H NMR reveals fine details of substrate specificity
S De Cesare, CA McKenna, N Mulholland… - Organic & …, 2021 - pubs.rsc.org
Amino acids are key synthetic building blocks that can be prepared in an enantiopure form
by biocatalytic methods. We show that the L-selective ornithine deacetylase ArgE catalyses …
by biocatalytic methods. We show that the L-selective ornithine deacetylase ArgE catalyses …
Development of phosphodiesterase–protein-kinase complexes as novel targets for discovery of inhibitors with enhanced specificity
Phosphodiesterases (PDEs) hydrolyze cyclic nucleotides to modulate multiple signaling
events in cells. PDEs are recognized to actively associate with cyclic nucleotide receptors …
events in cells. PDEs are recognized to actively associate with cyclic nucleotide receptors …