Acylcarnitines are fatty acid metabolites that play important roles in many cellular energy
metabolism pathways. They have historically been used as important diagnostic markers for …

The incidence of obesity and insulin resistance is growing, and the increase in type 2
diabetes mel-litus (DM2) constitutes one of the biggest challenges for our healthcare …

Abstract Background Schisandrin B (Sch B), which inhibits hepatic steatosis caused by non-
alcoholic fatty liver disease (NAFLD), is one of the most active dibenzocyclooctadienes …

Metabolites, the biochemical products of the cellular process, can be used to measure
alterations in biochemical pathways related to the pathogenesis of Alzheimer's disease …

Over the years, the mitochondrial fatty acid β-oxidation (FAO) pathway has been
characterised at the biochemical level as well as the molecular biological level. FAO plays a …

Obesity, characterized by expansion and metabolic dysregulation of white adipose tissue
(WAT), has reached pandemic proportions and acts as a primer for a wide range of …

Small synthetic molecules called growth hormone secretagogues (GHSs) stimulate the
release of growth hormone (GH) from the pituitary. They act through the GHS-R, a G protein …

Biotin-dependent carboxylases include acetyl-CoA carboxylase (ACC), propionyl-CoA
carboxylase (PCC), 3-methylcrotonyl-CoA carboxylase (MCC), geranyl-CoA carboxylase …

The number of individuals with prediabetes is expected to grow substantially and estimated
to globally affect 482 million people by 2040. Therefore, effective methods for diagnosing …

The etiology and pathophysiology of schizophrenia remain unknown. A parallel
transcriptomics, proteomics and metabolomics approach was employed on human brain …