CAR-T cell therapy in Multiple Myeloma: current status and future challenges

D Swan, D Madduri, J Hocking - Blood Cancer Journal, 2024 - nature.com
The treatment of multiple myeloma has changed dramatically in recent years, with huge
strides forward made in the field. Chimeric antigen receptor T-cell therapy targeting the B …

Charting the Course: Sequencing Immunotherapy for Multiple Myeloma

M Mohan, O Van Oekelen, OS Akhtar… - American Society of …, 2024 - ascopubs.org
Multiple chimeric antigen receptor (CAR) T-cell and bispecific antibody (bsAb) therapies
have been approved, demonstrating impressive clinical efficacy in relapsed/refractory …

Immune prognostic score predicts the risk of infection and survival outcomes in patients with relapsed multiple myeloma treated with bispecific antibodies

OS Akhtar, A Szabo, V Bhatlapenumarthi… - British Journal of …, 2024 - Wiley Online Library
The Glasgow prognostic score (GPS) and CAR‐HEMATOTOX (CAR‐HT) score identify
multiple myeloma (MM) patients at high risk for immune‐mediated toxicity and early mortality …

Incidence of Acute Kidney Injury in Relapsed and Refractory Multiple Myeloma treated with Teclistamab versus CAR T-cells

M Charkviani, MJV Brochero, A Mohan… - Nephrology Dialysis …, 2025 - academic.oup.com
Abstract Background and Hypothesis Teclistamab, a novel bispecific monoclonal antibody
targeting CD3 and B-cell maturation antigen (BCMA), and chimeric antigen receptor T-cell …

Myeloma CAR T-cell therapy toxicity timing: What is the right amount of post-treatment monitoring for our patients?

JN Brudno - … and Cellular Therapy, Official Publication of the …, 2024 - astctjournal.org
One additional non-relapse death occurring between 30 and 90 days after cell infusion was
attributed to infection. All deaths in the first 30 days occurred during the initial admission …