Multicomponent reactions for the synthesis of bioactive compounds: A review

CS Graebin, FV Ribeiro, KR Rogério… - Current Organic …, 2019 - ingentaconnect.com
Multicomponent reactions (MCRs) are composed of three or more reagents in which the final
product has all or most of the carbon atoms from its starting materials. These reactions …

Coumarin compounds in medicinal chemistry: some important examples from the last years

TM Pereira, DP Franco, F Vitorio… - Current topics in …, 2018 - ingentaconnect.com
Coumarins are natural products characterized as 1, 2 benzopyrones widely distributed in
plants, as well as, in many species of fungi and bacteria. Nowadays, many synthetic …

[PDF][PDF] Original and innovative advances in the synthetic schemes of coumarin-based derivatives: A review

YF Mustafa, MK Bashir, MK Oglah - Systematic Reviews in …, 2020 - researchgate.net
Coumarins reign their class term, which is the vulgarity name of the plant belongs to the
Fabaceae family named tonka bean. The parent compound, coumarin itself, was novally …

Efficient rapid access to Biginelli for the multicomponent synthesis of 1, 2, 3, 4-tetrahydropyrimidines in room-temperature diisopropyl ethyl ammonium acetate

CK Jadhav, AS Nipate, AV Chate, VD Songire… - ACS …, 2019 - ACS Publications
The diisopropyl ethyl ammonium acetate (DIPEAc)-promoted Biginelli protocol has been
developed for the first time by a successive one-pot three-component reaction of aldehydes …

Photoredox-Catalyzed Cascade Radical Cyclization of Ester Arylpropiolates with CF3SO2Cl To Construct 3-Trifluoromethyl Coumarin Derivatives

L Chen, L Wu, W Duan, T Wang, L Li… - The Journal of …, 2018 - ACS Publications
We report a highly efficient method to construct 3-trifluoromethyl coumarins using CF3SO2Cl
as the trifluoromethyl radical source with ester 3-arylpropiolates. The reaction incorporated a …

Hybrid 3, 4-dihydropyrimidin-2-(thi) ones as dual-functional bioactive molecules: fluorescent probes and cytotoxic agents to cancer cells

VP de Souza, FS Santos, FS Rodembusch… - New Journal of …, 2020 - pubs.rsc.org
A series of new hybrid fluorescent Biginelli compounds, including a Monastrol derivative,
were designed and synthesized with good yields. The photophysical studies revealed dual …

Multicomponent synthesis of chromophores–The one-pot approach to functional π-systems

L Brandner, TJJ Müller - Frontiers in Chemistry, 2023 - frontiersin.org
Multicomponent reactions, conducted in a domino, sequential or consecutive fashion, have
not only considerably enhanced synthetic efficiency as one-pot methodology, but they have …

Calix[n]arene-Catalyzed Three-Component Povarov Reaction: Microwave-Assisted Synthesis of Julolidines and Mechanistic Insights

PAS Abranches, WF de Paiva… - The Journal of …, 2018 - ACS Publications
A new one-pot cascade reaction-based application of Povarov reactions with ap-sulfonic
acid calix [4] arene catalyst for the synthesis of a series of 34 julolidine derivatives with …

MoO 2 Cl 2 catalyzed efficient synthesis of functionalized 3, 4-dihydropyrimidin-2 (1 H)-ones/thiones and polyhydroquinolines: recyclability, fluorescence and …

SD Guggilapu, SK Prajapti, A Nagarsenkar… - New Journal of …, 2016 - pubs.rsc.org
A simple, facile and efficient synthesis of functionalized dihydropyrimidinones and
polyhydroquinolines using molybdenum (VI) dichloride dioxide (MoO2Cl2) has been …

[HTML][HTML] A importância das cumarinas para a química medicinal eo desenvolvimento de compostos bioativos nos últimos anos

DP Franco, TM Pereira, F Vitorio, NF Nadur… - Química …, 2021 - SciELO Brasil
Coumarins are natural products characterized as 2H-chromen-2-one, according to IUPAC
nomenclature, largely distributed in plants, as well as, in species of fungi and bacteria …