HIV-exposed, uninfected infants: new global challenges in the era of paediatric HIV elimination

C Evans, CE Jones, AJ Prendergast - The Lancet infectious diseases, 2016 - thelancet.com
The number of infants infected with HIV is declining with the rise in interventions for the
elimination of paediatric HIV infection, but the number of uninfected infants exposed to HIV …

HIV treatment in pregnancy

H Bailey, R Zash, V Rasi, C Thorne - The lancet HIV, 2018 - thelancet.com
Almost 25 years since antiretroviral therapy (ART) was first shown to prevent mother-to-child
transmission of HIV, 76% of pregnant women living with HIV (over 1 million women) receive …

No perinatal HIV-1 transmission from women with effective antiretroviral therapy starting before conception

L Mandelbrot, R Tubiana, J Le Chenadec… - Clinical Infectious …, 2015 - academic.oup.com
Background. The efficacy of preventing perinatal transmission (PT) of human
immunodeficiency virus type 1 (HIV-1) depends on both viral load (VL) and treatment …

Cerebral vascular toxicity of antiretroviral therapy

L Bertrand, M Velichkovska, M Toborek - Journal of neuroimmune …, 2021 - Springer
HIV infection is associated with comorbidities that are likely to be driven not only by HIV
itself, but also by the toxicity of long-term use of antiretroviral therapy (ART). Indeed …

Evaluating neurodevelopmental consequences of perinatal exposure to antiretroviral drugs: current challenges and new approaches

JG Schnoll, B Temsamrit, D Zhang, H Song… - Journal of Neuroimmune …, 2021 - Springer
As antiretroviral therapy (ART) becomes increasingly affordable and accessible to women of
childbearing age across the globe, the number of children who are exposed to Human …

Health and survival of HIV perinatally exposed but uninfected children born to HIV-infected mothers

S Desmonde, T Goetghebuer, C Thorne… - Current Opinion in HIV …, 2016 - journals.lww.com
As we move toward the elimination of mother-to-child transmission of HIV, HEU children are
an emerging population whose health outcomes remain to be fully described. Future large …

Screening for HIV infection in pregnant women: updated evidence report and systematic review for the US Preventive Services Task Force

SS Selph, C Bougatsos, T Dana, S Grusing, R Chou - Jama, 2019 - jamanetwork.com
Importance Prenatal screening for HIV can inform use of interventions to reduce the risk of
mother-to-child transmission. The US Preventive Services Task Force (USPSTF) previously …

Safety of in-utero antiretroviral exposure: neurologic outcomes in children who are HIV-exposed but uninfected

CS Crowell, PL Williams, C Yildirim, RB Van Dyke… - Aids, 2020 - journals.lww.com
Objective: To evaluate whether there is an increased risk of neurologic diagnoses in
children who are HIV-exposed but uninfected (CHEU) exposed in utero to specific …

Prescribed opioid analgesics in early pregnancy and the risk of congenital anomalies: a population-based cohort study

AC Bowie, MM Werler, MP Velez, W Li, A Camden… - CMAJ, 2022 - Can Med Assoc
Background: Recent data suggest an increased risk of congenital anomalies with prenatal
exposure to opioid analgesics. We sought to further quantify the risk of anomalies after …

Zidovudine treatment in HIV-infected pregnant women is associated with fetal cardiac remodelling

L García-Otero, M López, O Gómez, A Goncé… - Aids, 2016 - journals.lww.com
Objective: To evaluate the cardiac structure and function of the fetuses of pregnant women
with HIV infection on combined antiretroviral treatment (cART) and the HIV-related and …