Mitochondria are recognized as one of the most important targets for new drug design in
cancer, cardiovascular, and neurological diseases. Currently, the most effective way to …

Conspectus Mitochondria are organelles with critical roles in key processes within
eukaryotic cells, and their dysfunction is linked with numerous diseases including …

One of the characteristics of cancer cells important for tumorigenesis is their metabolic
plasticity. Indeed, in various stress conditions, cancer cells can reshape their metabolic …

In recent years, mitochondrial medicine has emerged as a new discipline resting at the
intersection of mitochondrial biology, pathology, and pharmaceutics. The central role of …

An azobenzene scaffold serves as both a fluorescence quencher and nitrogen mustard
deactivator in a mitochondrial targeting unit bearing theranostic drug delivery system (DDS) …

Multidrug resistance (MDR) has been recognized as a major obstacle to successful
chemotherapy for cancer in the clinic. In recent years, more and more nanoscaled drug …

The mitochondrion is a very versatile organelle that participates in some important cancer‐
associated biological processes, including energy metabolism, oxidative stress …

Nullomers are the shortest strings of absent amino acid (aa) sequences in a species or
group of species. Primes are those nullomers that have not been detected in the genome of …

Mitochondria are multifunctional subcellular organelles whose operations encompass
energy production, signal transduction, and metabolic regulation. Given their wide range of …

The highly effective anticancer agent doxorubicin (Dox) is a frontline drug used to treat a
number of cancers. While Dox has a high level of activity against cancer cells, its clinical use …