Atypical antipsychotic drugs offer several notable benefits over typical antipsychotics,
including greater improvement in negative symptoms, cognitive function, prevention of …

The prevalence of diabetes mellitus is twofold to threefold higher in people with severe
mental illness (SMI) than in the general population, with diabetes mellitus affecting∼ 12% of …

Background Antipsychotic medications often have a variety of side effects, however, it is not
well understood how the presence of specific side effects correlate with adherence in a real …

Since the unexpected discovery of the antipsychotic activity of chlorpromazine, a variety of
therapeutic agents have been developed for the treatment of schizophrenia. Despite …

BackgroundThere are claims that second-generation antipsychotics produce fewer
extrapyramidal side-effects (EPS) compared with first-generation drugs. AimsTo compare …

The prevalence of overweight and obesity is higher in people with mental illness than in the
general population. Body weight is tightly regulated by a complex system involving the …

Abstract In 2005, the Remission in Schizophrenia Working Group published consensus
criteria to define remission. These criteria have been widely accepted and utilized and have …

This review summarizes the current state of knowledge regarding the proposed mechanisms
by which antipsychotic agents reduce the symptoms of schizophrenia while giving rise to …

Importance: Schizophrenia is a complex syndrome with taxing symptoms and for which
treatment challenges remain. Current dopamine D 2 receptor–blocking antipsychotics have …

It has been 50 years since the first patients with tardive dyskinesia (TD) were described, but
the pathophysiology is only partially understood and effective treatments have remained …