Achieving controlled biomolecule–biomaterial conjugation

CD Spicer, ET Pashuck, MM Stevens - Chemical reviews, 2018 - ACS Publications
The conjugation of biomolecules can impart materials with the bioactivity necessary to
modulate specific cell behaviors. While the biological roles of particular polypeptide …

Surface modification strategies for biomedical applications: enhancing cell–biomaterial interfaces and biochip performances

S Roh, Y Jang, J Yoo, H Seong - BioChip Journal, 2023 - Springer
Surface modification techniques are crucial in biomedical applications as they determine the
direct response to the biological environment against the interfacing materials. Physical and …

Aligned PCL fiber conduits immobilized with nerve growth factor gradients enhance and direct sciatic nerve regeneration

L Zhu, S Jia, T Liu, L Yan, D Huang… - Advanced functional …, 2020 - Wiley Online Library
Topographical guidance and chemotaxis are crucial factors for peripheral nerve
regeneration. This study describes the preparation of highly aligned poly (ε …

Biomaterials for sequestration of growth factors and modulation of cell behavior

SPB Teixeira, RMA Domingues… - Advanced Functional …, 2020 - Wiley Online Library
Growth factors (GFs) are proteins secreted by cells that regulate a variety of biological
processes. Although they have long been proposed as potent therapeutic agents, their …

Application of extracorporeal shock wave therapy in nervous system diseases: a review

J Guo, H Hai, Y Ma - Frontiers in Neurology, 2022 - frontiersin.org
Neurological disorders are one of the leading causes of morbidity and mortality worldwide,
and their therapeutic options remain limited. Recent animal and clinical studies have shown …

Layer-by-layer cell encapsulation for drug delivery: the history, technique basis, and applications

W Li, X Lei, H Feng, B Li, J Kong, M Xing - Pharmaceutics, 2022 - mdpi.com
The encapsulation of cells with various polyelectrolytes through layer-by-layer (LbL) has
become a popular strategy in cellular function engineering. The technique sprang up in …

Stemness maintenance and massproduction of neural stem cells on poly L‐lactic acid nanofibrous membrane based on piezoelectriceffect

X Lu, C Sun, L Chen, Z Feng, H Gao, S Hu, M Dong… - Small, 2022 - Wiley Online Library
Neural stem cells (NSCs) therapy is promising for treating neurodegenerative disorders and
neural injuries. However, the limited in vitro expansion, spontaneous differentiation, and …

FGF2-primed 3D spheroids producing IL-8 promote therapeutic angiogenesis in murine hindlimb ischemia

J Choi, W Choi, Y Joo, H Chung, D Kim… - NPJ Regenerative …, 2021 - nature.com
Peripheral artery disease is a progressive, devastating disease that leads to critical limb
ischemia (CLI). Therapeutic angiogenesis using stem cell therapy has emerged as a …

Investigations into the effects of scaffold microstructure on slow-release system with bioactive factors for bone repair

B Pei, M Hu, X Wu, D Lu, S Zhang, L Zhang… - … in Bioengineering and …, 2023 - frontiersin.org
In recent years, bone tissue engineering (BTE) has played an essential role in the repair of
bone tissue defects. Although bioactive factors as one component of BTE have great …

Subcutaneous priming of protein-functionalized chitosan scaffolds improves function following spinal cord injury

TR Ham, DD Pukale, M Hamrangsekachaee… - Materials Science and …, 2020 - Elsevier
Strategies using neural stem cells (NSCs) to aid regeneration following spinal cord injury
(SCI) show much promise, but challenges remain regarding implementation and efficacy. In …