Biomarker detection has attracted increasing interest in recent years due to the minimally or
non-invasive sampling process. Single entity analysis of biomarkers is expected to provide …

Protein is an important component of all the cells and tissues of the human body and is the
material basis of life. Its content, sequence, and spatial structure have a great impact on …

Natriuretic peptides can relieve cardiovascular stress and closely related to heart failure.
Besides, these peptides also have preferable interactions of binding to cellular protein …

Characteristic ionic current modulations will be produced in a single molecule manner
during the communication of individual molecules with a nanopore. Hence, the information …

Nanopore sensing is developing into a powerful label‐free approach to investigate the
features of biomolecules at the single‐molecule level. When a charged molecule is captured …

DNA triplex participates in delivering site-specific epigenetic modifications critical for the
regulation of gene expression. Among these marks, 5mC with 8oG functions …

Nanopore technology has attracted extensive attention due to its rapid, highly sensitive, and
label-free performance. In this study, we aimed to identify proteinogenic amino acids using a …

Nanopore is used as a single-molecule detector for proteins, peptides and amino acids
identification of biomedical importance. We, on the first try, extended its profiling application …

Nanopore stochastic sensing is a powerful analytical tool for detecting target molecules
through a nanoscale pore. The analyte and electrolyte ions are subjected to a voltage bias …

Anti-TNF IgG biotherapeutics are used to treat immune disorders such as rheumatoid
arthritis. They neutralise cytokine TNF-α to dampen the inflammatory response. These drugs …