Hypoxia plays an important role in the development of many infectious, inflammatory, and
tumor diseases. The predisposition to such disorders is mostly provided by differences in …

Introduction 2.1. Definitions 2.2. Scope 2.3. Objectives 3. Protein homeostasis 3.1. Life and
death of a protein 3.2. The chaperone molecule 3.3. Chaperoning teams 3.4. Chaperoning …

Environmentally induced periods of heat stress decrease productivity with devastating
economic consequences to global animal agriculture. Heat stress can be defined as a …

Background and Aims Costa Rica has among the highest incidence and mortality rates for
gastric cancer worldwide. The reasons for this are largely unknown. Polymorphisms of …

Noise-induced hearing loss (NIHL) is one of the most important occupational health
hazards. Millions of people worldwide are exposed daily to harmful levels of noise. NIHL is a …

Abstract MacInnis, Martin J., Michael S. Koehle, and Jim L. Rupert. Evidence for a genetic
basis for altitude illness: 2010 update. High Alt. Med. Biol. 11: 349–368, 2010.—Altitude …

Severe noise exposure can induce heat shock proteins (Hsps), and exposure to moderate
noise has been reported to confer protection against noise-induced damage to hearing …

Background Acute mountain sickness (AMS) is a potentially lethal condition caused by acute
hypoxia after ascending to altitudes higher than 2500 m in a short time. The main symptom …

Abstract Background: Heat shock protein 70 (Hsp70) has been shown to act as a chaperone
and be associated with a variety of tumors. We investigated HSP70-1 G+ 190C, HSP70-2 A+ …

Background Circulating heat shock protein 70 (Hsp70) is present in the circulation of healthy
individuals and in patients with various disorders, including chronic heart failure (CHF) …