Influences of the 3D microenvironment on cancer cell behaviour and treatment responsiveness: A recent update on lung, breast and prostate cancer models

LS Costard, RR Hosn, H Ramanayake, FJ O'Brien… - Acta Biomaterialia, 2021 - Elsevier
The majority of in vitro studies assessing cancer treatments are performed in two-
dimensional (2D) monolayers and are subsequently validated in in vivo animal models …

Recent Innovations in Strategies for Breast Cancer Therapy by Electrospun Scaffolds: A Review

S Ghaedamini, B Hashemibeni, A Honarvar… - Journal of Polymers and …, 2024 - Springer
The most commonly diagnosed cancer among women in the world is breast cancer. Despite
current treatment methods, new preventative and therapeutic strategies and development of …

Magnetic levitation assisted biofabrication, culture, and manipulation of 3D cellular structures using a ring magnet based setup

M Anil‐Inevi, K Delikoyun, G Mese… - Biotechnology and …, 2021 - Wiley Online Library
Diamagnetic levitation is an emerging technology for remote manipulation of cells in cell and
tissue level applications. Low‐cost magnetic levitation configurations using permanent …

Scaffold‐free biofabrication of adipocyte structures with magnetic levitation

O Sarigil, M Anil‐Inevi, B Firatligil‐Yildirir… - Biotechnology and …, 2021 - Wiley Online Library
Tissue engineering research aims to repair the form and/or function of impaired tissues.
Tissue engineering studies mostly rely on scaffold‐based techniques. However, these …

Quantitative approach for protein analysis in small cell ensembles by an integrated microfluidic chip with MALDI mass spectrometry

M Yang, J Cruz Villarreal, N Ariyasinghe… - Analytical …, 2021 - ACS Publications
Increasing evidence has demonstrated that cells are individually heterogeneous. Advancing
the technologies for single-cell analysis will improve our ability to characterize cells, study …

Colonization versus encapsulation in cell-laden materials design: porosity and process biocompatibility determine cellularization pathways

C Parisi, K Qin, FM Fernandes - … Transactions of the …, 2021 - royalsocietypublishing.org
Seeding materials with living cells has been—and still is—one of the most promising
approaches to reproduce the complexity and the functionality of living matter. The strategies …

[HTML][HTML] Decellularized fennel and dill leaves as possible 3D channel network in GelMA for the development of an in vitro adipose tissue model

F Grilli, M Pitton, L Altomare, S Farè - Frontiers in Bioengineering and …, 2022 - frontiersin.org
The development of 3D scaffold-based models would represent a great step forward in
cancer research, offering the possibility of predicting the potential in vivo response to …

Lung carcinoma spheroids embedded in a microfluidic platform

E Yildiz-Ozturk, P Saglam-Metiner, O Yesil-Celiktas - Cytotechnology, 2021 - Springer
Abstract Three-dimensional (3D) spheroid cell cultures are excellent models used in cancer
biology research and drug screening. The objective of this study was to develop a lung …

Stem cell culture under simulated microgravity

M Anil-Inevi, O Sarigil, M Kizilkaya, G Mese… - Cell Biology and …, 2020 - Springer
Challenging environment of space causes several pivotal alterations in living systems,
especially due to microgravity. The possibility of simulating microgravity by ground-based …

A Review on Multicellular Spheroids and Organoids for Breast Cancer Diagnosis and Therapy

S Jadhav, SN Rath, UK Roopavath - Biomedical Materials & Devices, 2024 - Springer
In response to escalating ethical and regulatory concerns surrounding animal testing in drug
development, regulatory bodies such as the Food and Drug Administration (FDA) have …