Neutrophils are innate immune phagocytes that have a central role in immune defence. Our
understanding of the role of neutrophils in pathogen clearance, immune regulation and …

The bacterial flagellum is an amazingly complex molecular machine with a diversity of roles
in pathogenesis including reaching the optimal host site, colonization or invasion …

Salmonella enterica serovar Typhimurium is a common facultative intracellular pathogen
that causes food‐borne gastroenteritis in millions of people worldwide. Intracellular survival …

Polymorphonuclear leukocytes (PMNs) are the most abundant white cell in humans and an
essential component of the innate immune system. PMNs are typically the first type of …

Lung metastases are the leading cause of death among cancer patients. The challenges of
inefficient drug delivery, compounded by a robust immunosuppressive microenvironment …

The biogenesis of the Salmonella‐containing vacuole within mammalian cells has been
intensively studied over recent years. However, the ability of Salmonella to sense and adapt …

Salmonella is a major foodborne pathogen and a leading cause of gastroenteritis in humans
and animals. Salmonella is highly pathogenic and encompasses more than 2600 …

Bacterial antitumor therapy has great application potential given its unique characteristics,
including genetic manipulation, tumor targeting specificity and immune system modulation …

SUMMARY A wide spectrum of pathogenic bacteria and protozoa has adapted to an
intracellular life-style, which presents several advantages, including accessibility to host cell …

Infection of intestinal epithelial cells is dependent on the Salmonella enterica serovar
Typhimurium pathogenicity island 1 (Spi1)-encoded type III injectisome system and flagellar …