The heterogeneity of tissue macrophages, in health and in disease, has become
increasingly transparent over the last decade. But with the plethora of data comes a natural …

Macrophages are innate immune cells that form a 3D network in all our tissues, where they
phagocytose dying cells and cell debris, immune complexes, bacteria and other waste …

The definition of gastrointestinal involvement in post-acute COVID-19 syndrome, its
frequency and its pathophysiology are still not completely understood. Here, we discuss the …

The gastrointestinal tract has the important task of absorbing nutrients, a complex process
that requires an intact barrier allowing the passage of nutrients but that simultaneously …

Inflammation must be tightly regulated to both defend against pathogens and restore tissue
homeostasis. The resolution of inflammatory responses is a dynamic process orchestrated …

The intestine harbors a large population of resident eosinophils, yet the function of intestinal
eosinophils has not been explored. Flow cytometry and whole-mount imaging identified …

Type 2 immunity is orchestrated by a canonical group of cytokines primarily produced by
innate lymphoid cells, group 2, and their adaptive counterparts, CD4+ helper type 2 cells …

Tissue immunity and responses to injury depend on the coordinated action and
communication among physiological systems. Here, we show that, upon injury, adaptive …

Correct development and maturation of the enteric nervous system (ENS) is critical for
survival. At birth, the ENS is immature and requires considerable refinement to exert its …

Resident tissue macrophages (RTMs) encompass a highly diverse set of cells abundantly
present in every tissue and organ. RTMs are recognized as central players in innate immune …