Introduction Topical drug delivery is highly attractive and yet faces tissue barrier challenges.
Different physical and chemical methods have been explored to facilitate topical drug …

The appropriate delivery of vaccines is a significant factor for the proper immunization. The
proper delivery of the cargo vaccine/antigen along with stimulation of high antigen mediated …

With the need for safe and efficacious vaccines which could be administered via non-
invasive procedure, alternatives to traditional injectables vaccines are sought after. The …

Abstract Respiratory Syncytial Virus (RSV) is one of the leading causes of bronchiolitis and
pneumonia in children under one year globally. As a result, RSV poses a severe burden on …

Psoriasis is an autoimmune skin disorder presenting the excessive expression of interleukin
(IL)-6. The topical use of small interfering RNA (siRNA) has been increasingly discovered for …

Retinoic acid (RA) is an approved treatment for skin photoaging induced by ultraviolet
(UVA). Topically applied RA is mainly located in the stratum corneum (SC) with limited …

Breast cancer is the number one cause of cancer-related deaths among females. Current
chemotherapy targets both tumor and normal cells, leading to pronounced side effects …

Delivering hydrosoluble compounds through the skin: what are the chances? -
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A favorable outcome of the COVID-19 crisis might be achieved with massive vaccination.
The proposed vaccines contain several different vaccine active principles (VAP), such as …

Although the global Zika epidemic in 2015–16 fueled vaccine development efforts, there is
no approved Zika vaccine or treatment available to date. Current vaccine platforms in clinical …