[HTML][HTML] Anti-thymocyte globulin as graft-versus-host disease prevention in the setting of allogeneic peripheral blood stem cell transplantation: a review from the Acute …
Allogeneic hematopoietic stem cell transplantation is increasingly used as treatment for
patients with life-threatening blood diseases. Its curative potential is largely based on …
patients with life-threatening blood diseases. Its curative potential is largely based on …
[HTML][HTML] Infusion of mesenchymal stromal cells after deceased liver transplantation: a phase I–II, open-label, clinical study
O Detry, M Vandermeulen, MH Delbouille, J Somja… - Journal of …, 2017 - Elsevier
Background & Aims Mesenchymal stromal cell (MSC) infusion could be a means to establish
tolerance in solid organ recipients. The aim of this prospective, controlled, phase I study was …
tolerance in solid organ recipients. The aim of this prospective, controlled, phase I study was …
[HTML][HTML] Infusion of third-party mesenchymal stromal cells after kidney transplantation: a phase I-II, open-label, clinical study
P Erpicum, L Weekers, O Detry, C Bonvoisin… - Kidney international, 2019 - Elsevier
Mesenchymal stromal cells (MSCs) exhibit anti-inflammatory and immune-regulatory
properties, and preclinical studies suggest a potential benefit in solid organ transplantation …
properties, and preclinical studies suggest a potential benefit in solid organ transplantation …
Methods of ex vivo expansion of human cord blood cells: challenges, successes and clinical implications
More than 40,000 unrelated cord blood transplantations (UCBT) have been performed
worldwide as treatment for patients with malignant or non-malignant life threatening …
worldwide as treatment for patients with malignant or non-malignant life threatening …
Xenogeneic graft-versus-host disease in humanized NSG and NSG-HLA-A2/HHD mice
G Ehx, J Somja, HJ Warnatz, C Ritacco… - Frontiers in …, 2018 - frontiersin.org
Despite the increasing use of humanized mouse models to study new approaches of graft-
versus-host disease (GVHD) prevention, the pathogenesis of xenogeneic GVHD (xGVHD) in …
versus-host disease (GVHD) prevention, the pathogenesis of xenogeneic GVHD (xGVHD) in …
Azacytidine prevents experimental xenogeneic graft-versus-host disease without abrogating graft-versus-leukemia effects
G Ehx, G Fransolet, L De Leval, S D'Hondt… - …, 2017 - Taylor & Francis
The demethylating agent 5-azacytidine (AZA) has proven its efficacy in the treatment of
myelodysplastic syndrome and acute myeloid leukemia. In addition, AZA can demethylate …
myelodysplastic syndrome and acute myeloid leukemia. In addition, AZA can demethylate …
[HTML][HTML] RIC versus MAC UCBT in adults with AML: a report from Eurocord, the ALWP and the CTIWP of the EBMT
Nonrelapse mortality (NRM) is the first cause of treatment failure after unrelated cord blood
transplantation (UCBT) following myeloablative conditioning (MAC). In the last decade …
transplantation (UCBT) following myeloablative conditioning (MAC). In the last decade …
Single-or double-unit UCBT following RIC in adults with AL: a report from Eurocord, the ALWP and the CTIWP of the EBMT
Background The feasibility of cord blood transplantation (CBT) in adults is limited by the
relatively low number of hematopoietic stem/progenitor cells contained in one single CB …
relatively low number of hematopoietic stem/progenitor cells contained in one single CB …
[HTML][HTML] Comprehensive analysis of the immunomodulatory effects of rapamycin on human T cells in graft-versus-host disease prophylaxis
G Ehx, C Ritacco, M Hannon, S Dubois… - American Journal of …, 2021 - Elsevier
Graft-versus-host disease (GVHD) is a major cause of toxicity after allogeneic hematopoietic
cell transplantation (allo-HCT). While rapamycin (RAPA) is commonly used in GVHD …
cell transplantation (allo-HCT). While rapamycin (RAPA) is commonly used in GVHD …
Novel approaches for preventing acute graft-versus-host disease after allogeneic hematopoietic stem cell transplantation
Introduction: Allogeneic hematopoietic stem cell transplantation (alloHSCT) offers potential
curative treatment for a wide range of malignant and nonmalignant hematological disorders …
curative treatment for a wide range of malignant and nonmalignant hematological disorders …