Recent update on nanoemulgel as topical drug delivery system

H Choudhury, B Gorain, M Pandey… - Journal of …, 2017 - Elsevier
Being an emerging transdermal delivery tool, nanoemulgel, has proved to show surprising
upshots for the lipophilic drugs over other formulations. This lipophilic nature of majority of …

Nanoemulgel: A promising phase in drug delivery

GC Aithal, R Narayan, UY Nayak - Current pharmaceutical …, 2020 - ingentaconnect.com
Recently, the delivery of hydrophobic/poorly water-soluble drugs has been a challenging
task. Various strategies have been developed to counter the former along with other prime …

Localized in situ nanoemulgel drug delivery system of quercetin for periodontitis: development and computational simulations

GC Aithal, UY Nayak, C Mehta, R Narayan… - Molecules, 2018 - mdpi.com
This study was aimed at formulating a bioabsorbable, controlled-release, nanoemulgel of
Quercetin, a potent antimicrobial and anti-inflammatory agent for the treatment of …

[HTML][HTML] A novel nanoformulation development of eugenol and their treatment in inflammation and periodontitis

N Ahmad, FJ Ahmad, S Bedi, S Sharma, S Umar… - Saudi Pharmaceutical …, 2019 - Elsevier
Objective To prepare a novel nanoemulsion-Carbopol® 934 gel for Eugenol, in order to
prevent the periodontitis. Material and methods Spontaneous emulsification method was …

[HTML][HTML] Anti-inflammatory effect of IL-1ra-loaded dextran/PLGA microspheres on Porphyromonas gingivalis lipopolysaccharide-stimulated macrophages in vitro and in …

B Ren, J Lu, M Li, X Zou, Y Liu, C Wang… - Biomedicine & …, 2021 - Elsevier
Periodontitis is a multifactorial chronic infectious disease leading to a host immune response
involving inflammatory cytokines, especially IL-1β, which is the main reason for further …

An enzyme-responsive membrane for antibiotic drug release and local periodontal treatment

N Li, L Jiang, H Jin, Y Wu, Y Liu, W Huang… - Colloids and Surfaces B …, 2019 - Elsevier
Periodontitis is a chronic, destructive inflammatory disease that injures tooth-supporting
tissues, eventually leading to tooth loss. Complete eradication of periodontal pathogenic …

The role of TLR4/MyD88/NF‐κB pathway in periodontitis‐induced liver inflammation of rats

Y Yue, X Liu, Y Li, B Xia, W Yu - Oral diseases, 2021 - Wiley Online Library
Objectives The aim of this study was to clarify the immune mechanism of hepatic injury
induced by periodontitis using a rat model. Methods Twenty‐four SPF male Wistar rats were …

Development and evaluation of minocycline hydrochloride-loaded in situ cubic liquid crystal for intra-periodontal pocket administration

Z Yang, X Liang, X Jiang, J Guo, Y Tao, S Wang, Y Cao… - Molecules, 2018 - mdpi.com
In the present study, an injectable in situ liquid crystal formulation was developed for local
delivery of minocycline hydrochloride (MH) for chronic periodontitis treatment. The …

Periodontal disease may induce liver fibrosis in an experimental study on Wistar rats

A Mester, L Ciobanu, M Taulescu… - Journal of …, 2019 - Wiley Online Library
Background The aim was to assess the effects of periodontal disease in promoting liver
fibrosis in a rat model of ligature‐induced periodontitis. Methods Twenty‐four Wistar rats …

Denervation effectively aggravates rat experimental periodontitis

X Yu, Z Gong, Q Lin, W Wang, S Liu… - Journal of periodontal …, 2017 - Wiley Online Library
Background Nerve and its related factors in the occurrence and development of periodontitis
are worthy of further study. Denervation research is a useful addition to nerve and …