Genetic backgrounds and diagnosis of familial hypercholesterolemia

J Rogozik, R Główczyńska, M Grabowski - Clinical Genetics, 2024 - Wiley Online Library
Lipid disorders play a critical role in the intricate development of atherosclerosis and its
clinical consequences, such as coronary heart disease and stroke. These disorders are …

Statin Use and Coronary Artery Calcification: a Systematic Review and Meta-analysis of Observational Studies and Randomized Controlled Trials

MN Shahraki, SM Jouabadi, D Bos, BH Stricker… - Current atherosclerosis …, 2023 - Springer
Abstract Purpose of Review This review aimed to determine the association between statin
use and coronary artery calcification (CAC), as detected by computed tomography in the …

Effectiveness of clinical scores in predicting coronary artery disease in familial hypercholesterolemia: a coronary computed tomography angiography study

F Catapano, N Galea, G Pambianchi, L D'Erasmo… - La radiologia …, 2023 - Springer
Purpose One of the major challenges in the management of familial hypercholesterolemia
(FH) is the stratification of cardiovascular risk in asymptomatic subjects. Our purpose is to …

Aortic Wall Thickness as a Surrogate for Subclinical Atherosclerosis in Familial and Nonfamilial Hypercholesterolemia: Quantitative 3D Magnetic Resonance Imaging …

R Gałąska, D Kulawiak-Gałąska, K Dorniak… - Journal of Clinical …, 2023 - mdpi.com
We aimed to compare the extent of subclinical atherosclerosis in the ascending and
descending aortas by measuring wall area and thickness using 3D cardiovascular magnetic …

[图书][B] Getting Low in Familial Hypercholesterolemia: Reducing LDL-C and a Lifetime of Cardiovascular Risk

M Davidson, A Liebeskind - 2021 - books.google.com
FH is marked by high levels of circulating LDL-C, leading to increased risk of premature
atherosclerotic cardiovascular disease (ASCVD). Patients frequently remain undiagnosed …