Tuberculosis treatment monitoring and outcome measures: new interest and new strategies
J Heyckendorf, SB Georghiou, N Frahm… - Clinical microbiology …, 2022 - Am Soc Microbiol
Despite the advent of new diagnostics, drugs and regimens, tuberculosis (TB) remains a
global public health threat. A significant challenge for TB control efforts has been the …
global public health threat. A significant challenge for TB control efforts has been the …
[HTML][HTML] Human tuberculosis and Mycobacterium tuberculosis complex: A review on genetic diversity, pathogenesis and omics approaches in host biomarkers …
Mycobacterium tuberculosis complex (MTBC) refers to a group of mycobacteria
encompassing nine members of closely related species that causes tuberculosis in animals …
encompassing nine members of closely related species that causes tuberculosis in animals …
Diagnostic biomarkers for active tuberculosis: progress and challenges
BMF Nogueira, S Krishnan… - EMBO Molecular …, 2022 - embopress.org
Tuberculosis (TB) is a leading cause of morbidity and mortality from a single infectious
agent, despite being preventable and curable. Early and accurate diagnosis of active TB is …
agent, despite being preventable and curable. Early and accurate diagnosis of active TB is …
[HTML][HTML] Heme oxygenase-1 modulates ferroptosis by fine-tuning levels of intracellular iron and reactive oxygen species of macrophages in response to Bacillus …
C Ma, X Wu, X Zhang, X Liu, G Deng - Frontiers in cellular and …, 2022 - frontiersin.org
Macrophages are the host cells and the frontline defense against of Mycobacterium
tuberculosis (Mtb) infection, and the form of death of infected macrophages plays a pivotal …
tuberculosis (Mtb) infection, and the form of death of infected macrophages plays a pivotal …
[HTML][HTML] Diagnosis and biomarkers for ocular tuberculosis: From the present into the future
Z Ludi, AA Sule, RP Samy, I Putera, B Schrijver… - Theranostics, 2023 - ncbi.nlm.nih.gov
Tuberculosis is an airborne disease caused by Mycobacterium tuberculosis (Mtb) and can
manifest both pulmonary and extrapulmonary disease, including ocular tuberculosis (OTB) …
manifest both pulmonary and extrapulmonary disease, including ocular tuberculosis (OTB) …
[HTML][HTML] Biomarkers as biomedical bioindicators: approaches and techniques for the detection, analysis, and validation of novel Biomarkers of diseases
A Ahmad, M Imran, H Ahsan - Pharmaceutics, 2023 - mdpi.com
A biomarker is any measurable biological moiety that can be assessed and measured as a
potential index of either normal or abnormal pathophysiology or pharmacological responses …
potential index of either normal or abnormal pathophysiology or pharmacological responses …
Conductive nano-gold self-assembled MXene@ hemin with high catalytic activity achieved by strong metal-support interactions: A powerful nanozyme for …
Y Chen, Y Gu, X Yi, H Huang, Y Li, B Yang… - Chemical Engineering …, 2023 - Elsevier
Despite multiple advances in tuberculosis (TB), there is still a lack of effective methods
available for its diagnosis. To this end, we developed a novel nanozyme-mediated …
available for its diagnosis. To this end, we developed a novel nanozyme-mediated …
[HTML][HTML] Pediatric tuberculosis management: a global challenge or breakthrough?
LNF Maphalle, BB Michniak-Kohn, MO Ogunrombi… - Children, 2022 - mdpi.com
Managing pediatric tuberculosis (TB) remains a public health problem requiring urgent and
long-lasting solutions as TB is one of the top ten causes of ill health and death in children as …
long-lasting solutions as TB is one of the top ten causes of ill health and death in children as …
[HTML][HTML] Revisiting the methods for detecting Mycobacterium tuberculosis: what has the new millennium brought thus far?
TA Campelo, PR Cardoso de Sousa… - Access …, 2021 - microbiologyresearch.org
Tuberculosis (TB) affects around 10 million people worldwide in 2019. Approximately 3.4%
of new TB cases are multidrug-resistant. The gold standard method for detecting …
of new TB cases are multidrug-resistant. The gold standard method for detecting …
CD38+CD27–TNF-α + on Mtb-specific CD4+ T Cells Is a Robust Biomarker for Tuberculosis Diagnosis
MP Acharya, SP Pradeep, VS Murthy… - Clinical Infectious …, 2021 - academic.oup.com
Background Early and accurate diagnosis followed by timely treatment are the key
prerequisites to fight tuberculosis (TB) and reduce its global burden. Despite scientific …
prerequisites to fight tuberculosis (TB) and reduce its global burden. Despite scientific …