Retroviruses infect a broad range of vertebrate hosts that includes amphibians, reptiles, fish,
birds and mammals. In addition, a typical vertebrate genome contains thousands of loci …

Endogenous retroviruses (ERVs) are evolutionary remnants of retroviral infections in which
the viral genome became embedded as a dormant regulatory element within the host …

The human genome contains a large number of retroviral elements acquired over the
process of evolution, some of which are specific to primates. However, as many of these are …

Long disregarded as junk DNA or genomic dark matter, endogenous retroviruses (ERVs)
have turned out to represent important components of the antiviral immune response. These …

Virus-derived sequences and transposable elements constitute a substantial portion of
many cellular genomes. Recent insights reveal the intimate evolutionary relationship …

In humans, retroviruses thrive more as symbionts than as parasites. Apart from the only two
modern exogenous human retroviruses (human T-cell lymphotropic and immunodeficiency …

Human endogenous retroviruses (HERVs) are the remnants of ancient retroviruses that
infected human germline cells and became integrated into the human genome millions of …

Background Amyotrophic lateral sclerosis (ALS) is a fatal neurodegenerative disorder. About
90% of ALS cases are without a known genetic cause. The human endogenous retrovirus …

The human genome harbors many endogenous retroviral elements, known as human
endogenous retroviruses (HERVs), which have been integrated into the genome during …

Retroviral infections are 'mini-symbiotic'events supplying recipient cells with sequences for
viral replication, including the reverse transcriptase (RT) and ribonuclease H (RNase H) …