The precise functional role of the hippocampus remains a topic of much debate. The
dominant view is that the dorsal (or posterior) hippocampus is implicated in memory and …

The hippocampal formation has been implicated in a growing number of disorders, from
Alzheimer's disease and cognitive ageing to schizophrenia and depression. How can the …

Identifying brain biomarkers of disease risk is a growing priority in neuroscience. The ability
to identify meaningful biomarkers is limited by measurement reliability; unreliable measures …

Deep brain stimulation (DBS) via implanted electrodes is used worldwide to treat patients
with severe neurological and psychiatric disorders. However, its invasiveness precludes …

We evaluate a fully automatic technique for labeling hippocampal subfields and cortical
subregions in the medial temporal lobe in in vivo 3 Tesla MRI. The method performs …

Multi-atlas segmentation is an effective approach for automatically labeling objects of
interest in biomedical images. In this approach, multiple expert-segmented example images …

Physical activity has been reported to improve cognitive function in humans and rodents,
possibly via a brain-derived neurotrophic factor (BDNF)-regulated mechanism. In this study …

As we grow older, we may grow wiser, but we can also experience memory loss and
cognitive slowing that can interfere with our daily routines. The cognitive neuroscience of …

A major mystery of many types of neurological and psychiatric disorders, such as
Alzheimer's disease (AD), remains the underlying, disease-specific neuronal damage …

▪ Abstract The medial temporal lobe includes a system of anatomically related structures that
are essential for declarative memory (conscious memory for facts and events). The system …