Dissolution methodology for taste masked oral dosage forms

S Gittings, N Turnbull, CJ Roberts… - Journal of controlled …, 2014 - Elsevier
Conventional adult dosage forms are often not suitable for the paediatric and geriatric
populations due to either swallowing difficulties or patient repulsion and a requirement for …

Taste masking approaches for medicines

W Faisal, F Farag, AAH Abdellatif… - Current drug delivery, 2018 - ingentaconnect.com
Undesirable taste is an important problem for patient compliance. Several oral
pharmaceuticals and bulking agents have disagreeable and bitter-tasting components. The …

In vitro and in vivo investigation of taste-masking effectiveness of Eudragit E PO as drug particle coating agent in orally disintegrating tablets

M Drašković, D Medarević, I Aleksić… - Drug development and …, 2017 - Taylor & Francis
Context: Considering that bitter taste of drugs incorporated in orally disintegrating tablets
(ODTs) can be the main reason for avoiding drug therapy, it is of the utmost importance to …

The Development of Eletriptan Hydrobromide Immediate Release Buccal Films Using Central Composite Rotatable Design: An In Vivo and In Vitro Approach

W Siddique, M Zaman, RM Sarfraz, MH Butt… - Polymers, 2022 - mdpi.com
The objective is to develop immediate release buccal films of Eletriptan Hydrobromide
(EHBR) using hydroxypropyl methylcellulose (HPMC) E5. The buccal films have the ability to …

Development of novel unfolding film system of Itopride hydrochloride using box-Behnken design—A gastro retentive approach

S Alaithan, NR Naveen, PS Goudanavar, PD Bhavani… - Pharmaceuticals, 2022 - mdpi.com
Currently, gastro-retentive dosage forms achieved a remarkable position among the oral
drug delivery systems. This is a broadly used technique to hold the drug delivery systems for …

Strategies for taste masking of orodispersible dosage forms: Time, concentration, and perception

J Yu, J Xie, H Xie, Q Hu, Z Wu, X Cai, Z Guo… - Molecular …, 2022 - ACS Publications
Orodispersible dosage forms, characterized as quick dissolving and swallowing without
water, have recently gained great attention from the pharmaceutical industry, as these forms …

pH-responsive delivery of rebaudioside a sweetener via mucoadhesive whey protein isolate core-shell nanocapsules

B Pomon, SM Davachi, P Li, M Arshadi… - Food …, 2022 - Elsevier
Rebaudioside (Reb A) is a natural high-intensity sweetener available for commercial use. Its
application has been hampered, however, by its unnatural sweetness profile and a bitter …

Development and in Vitro/In Vivo Evaluation of Itopride Hydrochloride Expanding Tablets

W Ahmed, RI El-Gogary, M Nasr… - Journal of Pharmaceutical …, 2023 - Springer
Purpose Gastroretentive drug delivery systems (GRDDS) have attracted interest for
enhancement of absorption and bioavailability of some drugs. Itopride hydrochloride (ITOP) …

Engineering of naproxen loaded polymer hybrid enteric microspheres for modified release tablets: development, characterization, in silico modelling and in vivo …

HA Hameed, S Khan, M Shahid, R Ullah… - Drug design …, 2020 - Taylor & Francis
Background Naproxen (NP) is a non-steroidal anti-inflammatory drug with poor aqueous
solubility and low oral bioavailability, which may lead to therapeutic failure. NP causes …

Microstructural investigation using synchrotron radiation X-ray microtomography reveals taste-masking mechanism of acetaminophen microspheres

Z Guo, X Yin, C Liu, L Wu, W Zhu, Q Shao… - International Journal of …, 2016 - Elsevier
The structure of solid drug delivery systems has considerable influence on drug release
behaviors from particles and granules and also impacts other properties relevant to release …