Neurophysiology in psychosis: The quest for disease biomarkers

B Wang, E Zartaloudi, JF Linden, E Bramon - Translational Psychiatry, 2022 - nature.com
Psychotic disorders affect 3% of the population at some stage in life, are a leading cause of
disability, and impose a great economic burden on society. Major breakthroughs in the …

Biotyping in psychosis: using multiple computational approaches with one data set

CA Tamminga, BA Clementz, G Pearlson… - …, 2021 - nature.com
Focusing on biomarker identification and using biomarkers individually or in clusters to
define biological subgroups in psychiatry requires a re-orientation from behavioral …

Genetic copy number variants, cognition and psychosis: a meta-analysis and a family study

JH Thygesen, A Presman, J Harju-Seppänen… - Molecular …, 2021 - nature.com
The burden of large and rare copy number genetic variants (CNVs) as well as certain
specific CNVs increase the risk of developing schizophrenia. Several cognitive measures …

[HTML][HTML] Amygdala hyperreactivity to faces conditioned with a social-evaluative meaning–a multiplex, multigenerational fMRI study on social anxiety endophenotypes

JM Bas-Hoogendam, H van Steenbergen… - NeuroImage: Clinical, 2020 - Elsevier
Social anxiety disorder (SAD) runs in families, but the neurobiological pathways underlying
the genetic susceptibility towards SAD are largely unknown. Here, we employed an …

Is auditory processing measured by the N100 an endophenotype for psychosis? A family study and a meta-analysis

B Wang, LJ Otten, K Schulze, H Afrah… - Psychological …, 2024 - cambridge.org
BackgroundThe N100, an early auditory event-related potential, has been found to be
altered in patients with psychosis. However, it is unclear if the N100 is a psychosis …

Accuracy of diagnostic classification algorithms using cognitive-, electrophysiological-, and neuroanatomical data in antipsychotic-naïve schizophrenia patients

BH Ebdrup, MC Axelsen, N Bak, B Fagerlund… - Psychological …, 2019 - cambridge.org
BackgroundA wealth of clinical studies have identified objective biomarkers, which separate
schizophrenia patients from healthy controls on a group level, but current diagnostic systems …

Endophenotypes of executive functions in obsessive compulsive disorder? A meta-analysis in unaffected relatives

E Zartaloudi, KR Laws, E Bramon - Psychiatric genetics, 2019 - journals.lww.com
Endophenotypes are mediator traits between genetic influences and clinical phenotypes.
Meta-analyses have consistently shown modest impairments of executive functioning in …

[HTML][HTML] Neurocognitive and neurophysiological endophenotypes in schizophrenia: An overview

FL Donati, A D'Agostino, F Ferrarelli - Biomarkers in neuropsychiatry, 2020 - Elsevier
Schizophrenia (SCZ) is a severe psychotic disorder that affects up to 1% of the US
population and it is associated with progressive impairment in social functioning and …

Trait disinhibition and NoGo event-related potentials in violent mentally disordered offenders and healthy controls

C Delfin, E Ruzich, M Wallinius, M Björnsdotter… - Frontiers in …, 2020 - frontiersin.org
Trait disinhibition may function as a dispositional liability toward maladaptive behaviors
relevant in the treatment of mentally disordered offenders (MDOs). Reduced amplitude and …

[HTML][HTML] Imaging the socially-anxious brain: recent advances and future prospects

JM Bas-Hoogendam, PM Westenberg - F1000Research, 2020 - ncbi.nlm.nih.gov
Social anxiety disorder (SAD) is serious psychiatric condition with a genetic background.
Insight into the neurobiological alterations underlying the disorder is essential to develop …