Exploitation of recombinant DNA and sequencing technologies has led to a new concept in
vaccination in which isolated epitopes, capable of stimulating a specific immune response …

Computational vaccinology includes epitope mapping, antigen selection, and immunogen
design using computational tools. Tools that facilitate the in silico prediction of immune …

Protein therapeutics hold a prominent and rapidly expanding place among medicinal
products. Purified blood products, recombinant cytokines, growth factors, enzyme …

A stabilized form of the respiratory syncytial virus (RSV) fusion (F) protein has been explored
as a vaccine to prevent viral infection because it presents several potent neutralizing …

Computational vaccine design, also known as computational vaccinology, encompasses
epitope mapping, antigen selection and immunogen design using computational tools. The …

Bone defects can originate from a variety of causes, including trauma, cancer, congenital
deformity, and surgical reconstruction. Success of the current “gold standard” treatment (ie …

Advances in the field of T cell immunology have contributed to the understanding that cross-
reactivity is an intrinsic characteristic of the T cell receptor (TCR), and that each TCR can …

With the development of novel vaccine strategies, T-cell epitope-based vaccines have
become promising prophylactic and therapeutic tools against infectious diseases that cannot …

Immunomodulation by nanoparticles, especially as related to the biochemical properties of
these unique materials, has scarcely been explored. In an in vitro model of human immunity …

MHC tetramers are an essential tool for characterizing antigen-specific CD4+ T cells.
However, their ex vivo analysis is limited by the large sample requirements. Here we …