Vascular endothelial cells: heterogeneity and targeting approaches

JK Hennigs, C Matuszcak, M Trepel, J Körbelin - Cells, 2021 - mdpi.com
Forming the inner layer of the vascular system, endothelial cells (ECs) facilitate a multitude
of crucial physiological processes throughout the body. Vascular ECs enable the vessel wall …

Prolonged sitting and peripheral vascular function: potential mechanisms and methodological considerations

EJ Pekas, MF Allen, SY Park - Journal of Applied …, 2023 - journals.physiology.org
Sitting time is associated with increased risks for subclinical atherosclerosis and
cardiovascular disease development, and this is thought to be partially due to sitting …

Impaired microcirculatory function, mitochondrial respiration, and oxygen utilization in skeletal muscle of claudicating patients with peripheral artery disease

SY Park, EJ Pekas, CP Anderson… - American Journal …, 2022 - journals.physiology.org
Peripheral artery disease (PAD) is an atherosclerotic disease that impairs blood flow and
muscle function in the lower limbs. A skeletal muscle myopathy characterized by …

Oxidative stress and vascular damage in the context of obesity: The hidden guest

E Martínez-Martínez, F V. Souza-Neto… - Antioxidants, 2021 - mdpi.com
The vascular system plays a central role in the transport of cells, oxygen and nutrients
between different regions of the body, depending on the needs, as well as of metabolic …

[HTML][HTML] Peripheral arterial disease: A small and large vessel problem

M Bethel, BH Annex - American Heart Journal Plus: Cardiology Research …, 2023 - Elsevier
Peripheral arterial disease (PAD) is one clinical manifestation of systemic atherosclerosis
and is very common. Despite its prevalence, PAD remains underdiagnosed, undertreated …

Pyridine nucleotide redox potential in coronary smooth muscle couples myocardial blood flow to cardiac metabolism

MM Dwenger, SM Raph, ML Reyzer… - Nature …, 2022 - nature.com
Adequate oxygen delivery to the heart during stress is essential for sustaining cardiac
function. Acute increases in myocardial oxygen demand evoke coronary vasodilation and …

Lipid emulsions inhibit labetalol-induced vasodilation in the isolated rat aorta

S Lee, KE Park, Y Hwang, S Bae, SH Ok… - International journal of …, 2024 - mdpi.com
Lipid emulsions are used as adjuvant drugs to alleviate intractable cardiovascular collapse
induced by drug toxicity. We aimed to examine the effect of lipid emulsions on labetalol …

Vascular smooth muscle cells can be circumferentially aligned inside a channel using tunable gelatin microribbons

Y Mastoor, M Karimi, M Sun, F Ahadi, P Mathieu… - …, 2024 - iopscience.iop.org
The gold standard to measure arterial health is vasodilation in response to nitric oxide.
Vasodilation is generally measured via pressure myography of arteries isolated from animal …

[HTML][HTML] Endothelial cell Piezo1 promotes vascular smooth muscle cell differentiation on large arteries

J Abello, Y Yin, Y Zhao, J Maurer, J Lee… - European journal of cell …, 2025 - Elsevier
Vascular stabilization is a mechanosensitive process, in part driven by blood flow. Here, we
demonstrate the involvement of the mechanosensitive ion channel, Piezo1, in promoting …

Visualization of Small Vessels by Micro–Computed Tomography Using Titanium Dioxide Nanoparticles as a Novel Contrast Agent

T Goto, R Tanabe, H Shibuya… - … Journal of Biomedical …, 2025 - Wiley Online Library
Angiography by means of micro–computed tomography (m‐CT) is extensively used for the
diagnosis of vasculature disorders. To establish a connection between m‐CT images and …