The predisposition of individuals to several common autoimmune diseases, such as
rheumatoid arthritis, systemic lupus erythematosus and multiple sclerosis, is genetically …

[Frontiers in Bioscience 7, d1056-1183, May 1, 2002] 1056 T CELLS AND AGING,
JANUARY 2002 UPDATE Graham Pawelec1, Yvonne Barnett Page 1 [Frontiers in …

Clonal composition and T cell receptor (TCR) repertoire of CD4+ and CD8+ T cells
infiltrating actively demyelinating multiple sclerosis (MS) lesions were determined with …

Epstein-Barr virus (EBV), a ubiquitous B-lymphotropic herpesvirus, has been associated
with multiple sclerosis (MS), an inflammatory disease of the central nervous system (CNS) …

Drug reaction with eosinophilia and systemic symptoms (DRESS) is a severe, drug-induced
reaction that involves both the skin and the viscera. Evidence for reactivation of herpes …

We surveyed the T cell receptor repertoire in three separate compartments (brain,
cerebrospinal fluid, and blood) of two multiple sclerosis patients who initially had diagnostic …

CD8+ T lymphocytes are a heterogeneous class of cells that play a crucial role in the
adaptive immune response against pathogens and cancer. During their lifetime, they …

The exact aetiology of most autoimmune diseases remains unknown, nonetheless, several
factors contributing to the induction or exacerbation of autoimmune reactions have been …

Human cytomegalovirus (HCMV) represents a prototypic pathogenic member of the β‐
subgroup of the herpesvirus family. A range of HCMV features like its lytic replication in …

Multiple sclerosis afflicts more than 1 million individuals worldwide and is widely considered
to be an autoimmune disease. Traditionally, CD4+ T helper cells have almost exclusively …