Autism spectrum disorder (ASD) comprises a heterogeneous group of neurodevelopmental
outcomes in children with a commonality in deficits in social communication and language …

In this article, we first present a summary of the general assumptions about Down syndrome
(DS) still to be found in the literature. We go on to show how new research has modified …

Down Syndrome (DS) entails an increased risk of many chronic diseases that are typically
associated with older age. The clinical manifestations of accelerated aging suggest that …

Conventional genetic testing of individuals with neurodevelopmental presentations and
congenital anomalies (ND/CAs), ie, the analysis of sequence and copy number variants …

DNA methylation is currently the most promising molecular marker for monitoring aging and
predicting life expectancy. However, the mechanisms underlying age-related DNA …

Background Prenatal alcohol exposure is the leading preventable cause of behavioral and
cognitive deficits, which may affect between 2 and 5% of children in North America. While …

Background—Genetic research regarding blood lipids has largely focused on DNA
sequence variation; few studies have explored epigenetic effects. Genome-wide surveys of …

The clinical and cytogenetic findings associated with mosaicism for trisomy 21/Down
syndrome are the focus of this review. The primary topics discussed in this overview of the …

Background Allergic disease affects 30% to 40% of the world's population, and its
development is determined by the interplay between environmental and inherited factors. Air …

Down syndrome (DS), also known as trisomy 21, is the most common genetic cause of
intellectual disability (ID). Although ID can be mild, the average intelligence quotient is in the …