Brain-derived neurotrophic factor (BDNF) is one of the most studied neurotrophins in the
healthy and diseased brain. As a result, there is a large body of evidence that associates …

Introduction Genetic data from the Alzheimer's Disease Neuroimaging Initiative (ADNI) have
been crucial in advancing the understanding of Alzheimer's disease (AD) pathophysiology …

Brain-derived neurotrophic factor (BDNF) has a neurotrophic support on neuron of central
nervous system (CNS) and is a key molecule in the maintenance of synaptic plasticity and …

Abstract The Alzheimer's Disease Neuroimaging Initiative (ADNI) is an ongoing,
longitudinal, multicenter study designed to develop clinical, imaging, genetic, and …

New neurons are generated throughout adulthood in two regions of the brain, the olfactory
bulb and dentate gyrus of the hippocampus, and are incorporated into the hippocampal …

Background Brain-derived neurotrophic factor (BDNF) is a neurotrophin involved in
neurogenesis and synaptic plasticity in the central nervous system, especially in the …

The hippocampus is one of the earliest affected brain regions in Alzheimer's disease (AD)
and its dysfunction is believed to underlie the core feature of the disease-memory …

Brain-derived neurotrophic factor (BDNF) gene regulation has been linked to the
pathophysiology of major depressive disorder (MDD). MDD patients show cognitive deficits …

Neurodegenerative disorders like Alzheimer's disease, Huntington's disease, Parkinson's
disease, spinocerebellar ataxias, amyotrophic lateral sclerosis, frontotemporal dementia to …

Objective: To examine the influence of the brain-derived neurotrophic factor (BDNF)
Val66Met polymorphism on longitudinal cognitive trajectories in a large, cognitively healthy …