The emerging roles of circRNAs in cancer and oncology
LS Kristensen, T Jakobsen, H Hager… - Nature reviews Clinical …, 2022 - nature.com
Over the past decade, circular RNAs (circRNAs) have emerged as a large class of primarily
non-coding RNA molecules, many of which have key roles in cancer development and …
non-coding RNA molecules, many of which have key roles in cancer development and …
CRISPR in cancer biology and therapy
Over the past decade, CRISPR has become as much a verb as it is an acronym,
transforming biomedical research and providing entirely new approaches for dissecting all …
transforming biomedical research and providing entirely new approaches for dissecting all …
CRISPR technologies for genome, epigenome and transcriptome editing
Our ability to edit genomes lags behind our capacity to sequence them, but the growing
understanding of CRISPR biology and its application to genome, epigenome and …
understanding of CRISPR biology and its application to genome, epigenome and …
Screening for functional circular RNAs using the CRISPR–Cas13 system
Circular RNAs (circRNAs) produced from back-spliced exons are widely expressed, but
individual circRNA functions remain poorly understood owing to the lack of adequate …
individual circRNA functions remain poorly understood owing to the lack of adequate …
Comparative multiplexed interactomics of SARS-CoV-2 and homologous coronavirus nonstructural proteins identifies unique and shared host-cell dependencies
JP Davies, KM Almasy, EF McDonald… - ACS infectious …, 2020 - ACS Publications
Human coronaviruses (hCoVs) have become a threat to global health and society, as
evident from the SARS outbreak in 2002 caused by SARS-CoV-1 and the most recent …
evident from the SARS outbreak in 2002 caused by SARS-CoV-1 and the most recent …
Human colorectal cancer-derived mesenchymal stem cells promote colorectal cancer progression through IL-6/JAK2/STAT3 signaling
Mesenchymal stem cells (MSCs) have been reported to localize in colorectal carcinomas,
and participate in the formation of the tumor microenvironment. They have recently been …
and participate in the formation of the tumor microenvironment. They have recently been …
Checkpoint blockade reverses anergy in IL-13Rα2 humanized scFv-based CAR T cells to treat murine and canine gliomas
Y Yin, AC Boesteanu, ZA Binder, C Xu, RA Reid… - Molecular Therapy …, 2018 - cell.com
We generated two humanized interleukin-13 receptor α2 (IL-13Rα2) chimeric antigen
receptors (CARs), Hu07BBz and Hu08BBz, that recognized human IL-13Rα2, but not IL …
receptors (CARs), Hu07BBz and Hu08BBz, that recognized human IL-13Rα2, but not IL …
[HTML][HTML] Identification of circular RNAs as a promising new class of diagnostic biomarkers for human breast cancer
L Lü, J Sun, P Shi, W Kong, K Xu, B He, S Zhang… - Oncotarget, 2017 - ncbi.nlm.nih.gov
Endogenous noncoding circular RNAs (circRNAs) have gained attention for their
involvement in carcinogenesis, but their expression pattern in breast cancer has remained …
involvement in carcinogenesis, but their expression pattern in breast cancer has remained …
[HTML][HTML] Interleukin 13 receptor alpha 2 (IL13Rα2): expression, signaling pathways and therapeutic applications in cancer
Abstract Interleukin 13 receptor alpha 2 (IL13Rα2) is increasingly recognized as a relevant
player in cancer invasion and metastasis. Despite being initially considered a decoy …
player in cancer invasion and metastasis. Despite being initially considered a decoy …
Regulation of Src family kinases during colorectal cancer development and its clinical implications
W Jin - Cancers, 2020 - mdpi.com
Src family kinases (SFKs) are non-receptor kinases that play a critical role in the
pathogenesis of colorectal cancer (CRC). The expression and activity of SFKs are …
pathogenesis of colorectal cancer (CRC). The expression and activity of SFKs are …