Exploring the role of Azadirachta indica (neem) and its active compounds in the regulation of biological pathways: an update on molecular approach

S Sarkar, RP Singh, G Bhattacharya - 3 Biotech, 2021 - Springer
In ethnomedicine, plant parts and compounds are used traditionally to treat different
diseases. Neem (Azadirachta indica A. Juss) is the most versatile and useful medicinal plant …

Neem components as potential agents for cancer prevention and treatment

F Hao, S Kumar, N Yadav, D Chandra - Biochimica et Biophysica Acta (BBA …, 2014 - Elsevier
Azadirachta indica, also known as neem, is commonly found in many semi-tropical and
tropical countries including India, Pakistan, and Bangladesh. The components extracted …

Growth inhibitory and chemo-sensitization effects of naringenin, a natural flavanone purified from Thymus vulgaris, on human breast and colorectal cancer

MSI Abaza, KY Orabi, E Al-Quattan… - Cancer cell international, 2015 - Springer
Background Natural products with diverse bioactivities are becoming an important source of
novel agents with medicinal potential. Cancer is a devastating disease that causes the death …

[HTML][HTML] Natural radioprotectors and their impact on cancer drug discovery

V Kuruba, P Gollapalli - Radiation oncology journal, 2018 - ncbi.nlm.nih.gov
Cancer is a complex multifaceted illness that affects different patients in discrete ways. For a
number of cancers the use of chemotherapy has become standard practice. Chemotherapy …

The anti-cancer properties of neem (Azadirachta indica) through its antioxidant activity in the liver: its pharmaceutics and toxic dosage forms. A literature review

M Iman, M Taheri, Z Bahari - Journal of Complementary and …, 2022 - degruyter.com
Objectives The neem (Azadirachta indica) have been used in herbal medicine for the
treatment of multiple diseases, particularly cancer. The mechanism of anti-cancer properties …

[HTML][HTML] Exploring the therapeutic potential of Neem (Azadirachta Indica) for the treatment of prostate cancer: a literature review

N Batra, VE Kumar, R Nambiar… - Annals of …, 2022 - ncbi.nlm.nih.gov
Exploring the therapeutic potential of Neem (Azadirachta Indica) for the treatment of prostate
cancer: a literature review - PMC Back to Top Skip to main content NIH NLM Logo Access keys …

Ethanolic Neem (Azadirachta indica) Leaf Extract Prevents Growth of MCF‐7 and HeLa Cells and Potentiates the Therapeutic Index of Cisplatin

C Sharma, AJ Vas, P Goala, TM Gheewala… - Journal of …, 2014 - Wiley Online Library
The present study was designed to gain insight into the antiproliferative activity of ethanolic
neem leaves extract (ENLE) alone or in combination with cisplatin by cell viability assay on …

The prospective role of plant products in radiotherapy of cancer: a current overview

B Hazra, S Ghosh, A Kumar, BN Pandey - Frontiers in pharmacology, 2012 - frontiersin.org
Treatment of cancer often requires exposure to radiation, which has several limitations
involving non-specific toxicity toward normal cells, reducing the efficacy of treatment. Efforts …

A supercritical CO2 extract of neem leaf (A. indica) and its bioactive liminoid, nimbolide, suppresses colon cancer in preclinical models by modulating pro …

MJ Patel, S Tripathy, KD Mukhopadhyay… - Molecular …, 2018 - Wiley Online Library
Colorectal cancer (CRC) is the third most commonly diagnosed cancer and the second
leading cause of cancer death in men and women in the United States. Anti‐inflammatory …

Screening of Azadirachta indica phytoconstituents as GSK-3β inhibitor and its implication in neuroblastoma: molecular docking, molecular dynamics, MM-PBSA …

S Chandel, R Singh, A Gautam… - Journal of Biomolecular …, 2022 - Taylor & Francis
Abstract Glycogen synthase kinase-3 (GSK-3), a constitutively active serine/threonine
kinase, primary regulator of various cellular activities varying from glycogen metabolism to …