Inflammatory bowel disease (IBD) comprises ulcerative colitis (UC) and Crohn's disease
(CD). IBD etiopathology is multifactorial and involves alteration of immune cells and chronic …

Glucocorticoids are hormones that regulate several functions in living organisms and
synthetic glucocorticoids are the most powerful anti-inflammatory pharmacological tool that …

For more than 70 years, glucocorticoids (GCs) have been a powerful and affordable
treatment option for inflammatory diseases. However, their benefits do not come without a …

The complex pathogenesis of inflammatory bowel disease (IBD) explains the several
hurdles for finding an efficient approach to cure it. Nowadays, therapeutic protocols aim to …

Efficient clearance of dying cells (efferocytosis) is an evolutionarily conserved process for
tissue homeostasis. Genetic enhancement of efferocytosis exhibits therapeutic potential for …

Background Pharmacological corticosteroid therapy is the standard of care in Duchenne
Muscular Dystrophy (DMD) that aims to control symptoms and slow disease progression …

Chronic inflammatory diseases including human immunodeficiency virus infection, psoriasis,
rheumatoid arthritis, and systemic lupus erythematosus predispose to atherosclerotic …

Nowadays, non-biological treatments remain valuable approaches among the therapeutic
armamentarium of inflammatory bowel disease (IBD). Mesalamine is the core treatment of …

Inflammatory bowel disease (IBD) is characterized as chronic inflammation in the
gastrointestinal tract, which includes two main subtypes, Crohn's disease and ulcerative …

Janus kinase (JAK) inhibitors, also known as jakinibs, are third-generation oral small
molecules that have expanded the therapeutic options for the management of chronic …