Early brain development, from the embryonic period to infancy, is characterized by rapid
structural and functional changes. These changes can be studied using structural and …

Early interventions for autism spectrum disorder (ASD) are increasingly available, while only
42–50% of ASD children are diagnosed before 3 years old (YO). To identify neuroimaging …

Background Secondary and retrospective use of hospital-hosted clinical data provides a
time-and cost-efficient alternative to prospective clinical trials for biomarker development …

Rett syndrome (RTT) is a rare congenital disorder which in most cases (95%) is caused by
methyl-CpG binding protein 2 (MECP2) mutations. RTT is characterized by regression in …

Network based medical data computing and collaborative visualization have been
commonly used in remote medicine and distributed diagnosis, where visualizing 3D medical …

Background Down syndrome (DS) is the most prevalent chromosomal disorder
characterized by intellectual disability, multiple organ anomalies, generalized muscular …

PTEN hamartoma tumor syndrome (PHTS) is a spectrum of hereditary cancer syndromes
caused by germline mutations in PTEN. PHTS is of high interest, because of its high rate of …

Patients with sensorineural hearing loss (SNHL) tend to show language delay, executive
functioning deficits, and visual cognitive impairment, even after intervention with hearing …

Developmental changes that occur before birth are thought to be associated with the
development of autism spectrum disorders. Identifying anatomical predictors of early brain …

Introduction Secondary analysis of hospital-hosted clinical data can save time and cost
compared with prospective clinical trials for neuroimaging biomarker development. We …