With the development of nanotechnology, nanomedicines are widely used in tumor therapy.
However, biological barriers in the delivery of nanoparticles still limit their application in …

The proposal of gene therapy to tackle cancer development has been instrumental for the
development of novel approaches and strategies to fight this disease, but the efficacy of the …

Despite that great progression has been made in nanoparticulate drug delivery systems
(nano-DDS), multiple drug delivery dilemmas still impair the delivery efficiency of …

Tannins are a heterogenous class of polyphenolic natural products with promising cancer
chemopreventive and therapeutic potential. Studies undertaken over the last 30 years have …

Although bone tissues possess an intrinsic capacity for repair, there are cases where bone
healing is either impaired or insufficient, such as fracture non-union, osteoporosis …

Abstract Purpose of Review This short review is aimed at providing an updated and
comprehensive report on tannic acid biological activities and molecular mechanisms of …

A series of barriers including poor drug solubility, stability, biocompatibility, bioavailability
and pharmacokinetics, distribution to normal tissues, hemorheological flow limitations …

Nanomedicines for antitumour therapy have been widely studied in recent decades, but only
a few have been used in clinical applications. One of the most important reasons is the poor …

As emerging tumor components, intratumoral bacteria have been found in many solid
tumors. Several studies have demonstrated that different cancer subtypes have distinct …

Initially, metal derived nanoparticles have been used exclusively as contrasting agents in
magnetic resonance imaging. Today, green routes of chemical synthesis together with …