Gene-environment interactions in schizophrenia: a literature review

MH Wahbeh, D Avramopoulos - Genes, 2021 - mdpi.com
Schizophrenia is a devastating mental illness with a strong genetic component that is the
subject of extensive research. Despite the high heritability, it is well recognized that non …

Applications of artificial intelligence− machine learning for detection of stress: a critical overview

AFA Mentis, D Lee, P Roussos - Molecular Psychiatry, 2024 - nature.com
Psychological distress is a major contributor to human physiology and pathophysiology, and
it has been linked to several conditions, such as auto-immune diseases, metabolic …

[HTML][HTML] Early social adversity, altered brain functional connectivity, and mental health

NE Holz, O Berhe, S Sacu, E Schwarz, J Tesarz… - Biological …, 2023 - Elsevier
Early adverse environmental exposures during brain development are widespread risk
factors for the onset of severe mental disorders and strong and consistent predictors of …

Polygenic risk scores for predicting outcomes and treatment response in psychiatry: hope or hype?

L Fusar-Poli, BPF Rutten, J van Os… - … Review of Psychiatry, 2022 - Taylor & Francis
Over the last years, the decreased costs and enhanced accessibility to large genome-wide
association studies datasets have laid the foundations for the development of polygenic risk …

[HTML][HTML] Gender differences in the association between environment and psychosis

AY Pence, LK Pries, M Ferrara, BPF Rutten… - Schizophrenia …, 2022 - Elsevier
Various environmental exposures have been associated with psychosis spectrum disorder.
However, the role of gender in this association has received little attention. Therefore, we …

Need for ethnic and population diversity in psychosis research

C Burkhard, S Cicek, R Barzilay… - Schizophrenia …, 2021 - academic.oup.com
This article aims to evaluate “racial”, ethnic, and population diversity—or lack thereof—in
psychosis research, with a particular focus on socio-environmental studies. Samples of …

Schizophrenia and the environment: within-person analyses may be required to yield evidence of unconfounded and causal association—the example of cannabis …

J Van Os, LK Pries, M Ten Have, R de Graaf… - Schizophrenia …, 2021 - academic.oup.com
Hypotheses about the link between cannabis use and psychosis apply to the within-person
level but have been tested mostly at the between-person level. We used a within-person …

Early marriage, stressful life events and risk of suicide and suicide attempt: a case–control study in Iran

A Fakhari, H Allahverdipour, ED Esmaeili, VK Chattu… - BMC psychiatry, 2022 - Springer
Abstract Background Early Marriage (EM) and associated Stressful Life Events (SLEs) and
consequences such as psychological and physical well-being issues can lead to suicide …

Examining the independent and joint effects of genomic and exposomic liabilities for schizophrenia across the psychosis spectrum

LK Pries, GA Dal Ferro, J van Os… - Epidemiology and …, 2020 - cambridge.org
AimsPsychosis spectrum disorder has a complex pathoetiology characterised by interacting
environmental and genetic vulnerabilities. The present study aims to investigate the role of …

Deconstructing the role of the exposome in youth suicidal ideation: Trauma, neighborhood environment, developmental and gender effects

R Barzilay, TM Moore, ME Calkins, L Maliackel… - Neurobiology of …, 2021 - Elsevier
Environment (E) is pivotal in explaining variability in brain and behavior development,
including suicidal ideation (SI) and behavior. It is therefore critical to systematically study …