The role of thiols in antioxidant systems
The sulfur biochemistry of the thiol group endows cysteines with a number of highly
specialized and unique features that enable them to serve a variety of different functions in …
specialized and unique features that enable them to serve a variety of different functions in …
SIRT1 and SIRT6 signaling pathways in cardiovascular disease protection
N D'Onofrio, L Servillo, ML Balestrieri - Antioxidants & redox …, 2018 - liebertpub.com
Significance: Oxidative stress represents the common hallmark of pathological conditions
associated with cardiovascular disease (CVD), including atherosclerosis, heart failure …
associated with cardiovascular disease (CVD), including atherosclerosis, heart failure …
The biology of ergothioneine, an antioxidant nutraceutical
Ergothioneine (ERG) is an unusual thio-histidine betaine amino acid that has potent
antioxidant activities. It is synthesised by a variety of microbes, especially fungi (including in …
antioxidant activities. It is synthesised by a variety of microbes, especially fungi (including in …
Administration of pure ergothioneine to healthy human subjects: uptake, metabolism, and effects on biomarkers of oxidative damage and inflammation
IK Cheah, RMY Tang, TSZ Yew, KHC Lim… - Antioxidants & redox …, 2017 - liebertpub.com
Aim: We investigated the uptake and pharmacokinetics of l-ergothioneine (ET), a dietary
thione with free radical scavenging and cytoprotective capabilities, after oral administration …
thione with free radical scavenging and cytoprotective capabilities, after oral administration …
Distribution and accumulation of dietary ergothioneine and its metabolites in mouse tissues
RMY Tang, IKM Cheah, TSK Yew, B Halliwell - Scientific reports, 2018 - nature.com
L-ergothioneine (ET) is a diet-derived amino acid that accumulates at high concentrations in
animals and humans. Numerous studies have highlighted its antioxidant abilities in vitro …
animals and humans. Numerous studies have highlighted its antioxidant abilities in vitro …
Could ergothioneine aid in the treatment of coronavirus patients?
IK Cheah, B Halliwell - Antioxidants, 2020 - mdpi.com
Infection with SARS-CoV-2 causes the coronavirus infectious disease 2019 (COVID-19), a
pandemic that has, at present, infected more than 11 million people globally. Some COVID …
pandemic that has, at present, infected more than 11 million people globally. Some COVID …
Low plasma ergothioneine levels are associated with neurodegeneration and cerebrovascular disease in dementia
Ergothioneine (ET) is a dietary amino-thione with strong antioxidant and cytoprotective
properties and has possible therapeutic potential for neurodegenerative and vascular …
properties and has possible therapeutic potential for neurodegenerative and vascular …
Ergothioneine oxidation in the protection against high-glucose induced endothelial senescence: involvement of SIRT1 and SIRT6
N D'Onofrio, L Servillo, A Giovane, R Casale… - Free Radical Biology …, 2016 - Elsevier
Ergothioneine (Egt), the betaine of 2-mercapto-L-histidine, is a dietary antioxidant protecting
against many diseases, including cardiovascular disease (CVD), through a redox …
against many diseases, including cardiovascular disease (CVD), through a redox …
Ergothioneine, an adaptive antioxidant for the protection of injured tissues? A hypothesis
Ergothioneine (ET) is a diet-derived, thiolated derivative of histidine with antioxidant
properties. Although ET is produced only by certain fungi and bacteria, it can be found at …
properties. Although ET is produced only by certain fungi and bacteria, it can be found at …
Role of ergothioneine in microbial physiology and pathogenesis
BM Cumming, KC Chinta, VP Reddy… - Antioxidants & Redox …, 2018 - liebertpub.com
Significance: L-ergothioneine is synthesized in actinomycetes, cyanobacteria,
methylobacteria, and some fungi. In contrast to other low-molecular-weight redox buffers …
methylobacteria, and some fungi. In contrast to other low-molecular-weight redox buffers …