The tetrahydrofuran motif in marine lipids and terpenes

P González-Andrés, L Fernández-Peña, C Díez-Poza… - Marine drugs, 2022 - mdpi.com
Heterocycles are particularly common moieties within marine natural products. Specifically,
tetrahydrofuranyl rings are present in a variety of compounds which present complex …

Marine Natural Products Rescuing the Eye: A Narrative Review

F Lixi, L Vitiello, G Giannaccare - Marine Drugs, 2024 - mdpi.com
Different degrees of visual impairment lead to a decrease in patient wellbeing, which has an
adverse effect on many facets of social and professional life. Eye disorders can affect …

Antiprotozoal activities of marine polyether triterpenoids

AR Díaz-Marrero, A López-Arencibia… - Bioorganic …, 2019 - Elsevier
Chagas disease and leishmaniasis are tropical neglected diseases caused by
kinetoplastids protozoan parasites of Trypanosoma and Leishmania genera, and a public …

[HTML][HTML] Gongolarones as antiamoeboid chemical scaffold

RL Rodríguez-Expósito… - Biomedicine & …, 2023 - Elsevier
Abstract Free Living Amoeba (FLA) infections caused by Acanthamoeba genus include
chronic nervous system diseases such as Granulomatous Amoebic Encephalitis (GAE), or a …

Laurequinone, a Lead Compound against Leishmania

S García-Davis, A López-Arencibia… - Marine Drugs, 2023 - mdpi.com
Among neglected tropical diseases, leishmaniasis is one of the leading causes, not only of
deaths but also of disability-adjusted life years. This disease, caused by protozoan parasites …

In Vitro Activity of Statins against Naegleria fowleri

A Rizo-Liendo, I Sifaoui, M Reyes-Batlle, O Chiboub… - Pathogens, 2019 - mdpi.com
Naegleria fowleri causes a deadly disease called primary amoebic meningoencephalitis
(PAM). Even though PAM is still considered a rare disease, the number of reported cases …

[HTML][HTML] Cyclolauranes as plausible chemical scaffold against Naegleria fowleri

I Arberas-Jimenez, S García-Davis… - Biomedicine & …, 2022 - Elsevier
Primary amoebic meningoencephalitis (PAM) is a central nervous system (CNS) disease
caused by Naegleria fowleri that mainly affects children and young adults with fatal …

[HTML][HTML] Fluvastatin and atorvastatin induce programmed cell death in the brain eating amoeba Naegleria fowleri

A Rizo-Liendo, I Sifaoui, I Arberas-Jiménez… - Biomedicine & …, 2020 - Elsevier
Naegleria fowleri is the causative agent of a type of encephalitis called Primary Amoebic
Encephalitis (PAM). Almost 98% of PAM cases reported worldwide are fatal and affect …

Combating the causative agent of amoebic keratitis, Acanthamoeba castellanii, using Padina pavonica alcoholic extract: toxicokinetic and molecular docking …

SS Abdel-Hakeem, FAM Hassan, AF Hifney… - Scientific Reports, 2024 - nature.com
Natural products play a significant role in providing the current demand as antiparasitic
agents, which offer an attractive approach for the discovery of novel drugs. The present …

Chamigrane-Type Sesquiterpenes from Laurencia dendroidea as Lead Compounds against Naegleria fowleri

I Arberas-Jiménez, N Nocchi, J Chao-Pellicer, I Sifaoui… - Marine Drugs, 2023 - mdpi.com
Naegleria fowleri is an opportunistic protozoon that can be found in warm water bodies. It is
the causative agent of the primary amoebic meningoencephalitis. Focused on our interest to …