Role of the insulin-like growth factor family in cancer development and progression

H Yu, T Rohan - Journal of the National Cancer Institute, 2000 - academic.oup.com
The insulin-like growth factors (IGFs) are mitogens that play a pivotal role in regulating cell
proliferation, differentiation, and apoptosis. The effects of IGFs are mediated through the IGF …

Energy balance and cancer: the role of insulin and insulin-like growth factor-I

R Kaaks, A Lukanova - Proceedings of the nutrition society, 2001 - cambridge.org
Recent theories propose that a Western lifestyle may increase cancer risk through
alterations in the metabolism of insulin and insulin-like growth factors (IGF; McKeown …

Serum levels of insulin-like growth factor I and its binding proteins in health and disease

A Juul - Growth hormone & IGF research, 2003 - Elsevier
Postnatal growth and development of the human body and its specific organs are regulated
by a complex network of local and systemic factors which is poorly understood. This review …

The growth hormone/insulin-like growth factor-I axis in exercise and sport

J Gibney, ML Healy, PH Sönksen - Endocrine reviews, 2007 - academic.oup.com
The syndrome of adult GH deficiency and the effects of GH replacement therapy provide a
useful model with which to study the effects of the GH/IGF-I axis on exercise physiology …

Serum levels of total and free IGF-I and IGFBP-3 are increased and maintained in long-term training

LP Koziris, RC Hickson… - Journal of applied …, 1999 - journals.physiology.org
The goals of this study were to determine whether the long-term training regimens
experienced by competitive collegiate swimmers would result in altered levels of total and …

Endogenous anabolic hormone responses to endurance versus resistance exercise and training in women

LA Consitt, JL Copeland, MS Tremblay - Sports Medicine, 2002 - Springer
Research in exercise endocrinology has flourished over the past few decades. In general,
research examining short-and long-term hormone responses to endurance exercise …

Exercise modulates insulin-like growth factor 1-dependent and-independent effects on adult hippocampal neurogenesis and behaviour

M LLorens-Martín, I Torres-Alemán, JL Trejo - Molecular and Cellular …, 2010 - Elsevier
While physical exercise clearly has beneficial effects on the brain, fomenting
neuroprotection as well as promoting neural plasticity and behavioural modifications, the …

Overnight responses of the circulating IGF-I system after acute, heavy-resistance exercise

BC Nindl, WJ Kraemer, JO Marx… - Journal of applied …, 2001 - journals.physiology.org
This study evaluated the individual components of the insulin-like growth factor I (IGF-I)
system [ie, total and free IGF-I, insulin-like growth factor binding protein (IGFBP)-2 and-3 …

Brain repair and neuroprotection by serum insulin-like growth factor I

E Carro, JL Trejo, A Núñez, I Torres-Aleman - Molecular neurobiology, 2003 - Springer
The existence of protective mechanisms in the adult brain is gradually being recognized as
an important aspect of brain function. For many years, self-repair processes in the post …

[PDF][PDF] High-affinity growth hormone binding protein and acute heavy resistance exercise

MR Rubin, WJ Kraemer, CM Maresh… - Medicine & Science in …, 2005 - academia.edu
ABSTRACT RUBIN, MR, WJ KRAEMER, CM MARESH, JS VOLEK, NA RATAMESS, JL
VANHEEST, R. SILVESTRE, DN FRENCH, MJ SHARMAN, DA JUDELSON, AL GOMEZ, JD …