• The specific situation of the patient. Unless otherwise provided for by national regulations,
off-label use of medication should be limited to situations where it is in the patient's interest …

Aortic dissection is a life-threatening condition caused by a tear in the intimal layer of the
aorta or bleeding within the aortic wall, resulting in the separation (dissection) of the layers …

Abstract Aim The “2022 ACC/AHA Guideline for the Diagnosis and Management of Aortic
Disease” provides recommendations to guide clinicians in the diagnosis, genetic evaluation …

Aims The incidence of acute aortic dissection (AAD) has been shown to have seasonal
variation, but whether this variation can be explained by non-optimum ambient temperature …

Aortic dissection continues to be responsible for significant morbidity and mortality, although
recent advances in medical data assimilation and in experimental and in silico models have …

Aortic dissection and intramural haematoma comprise an aortopathy involving separation of
the aortic wall. Underlying mechanisms of the condition remain unclear. Here we show that …

Abstract Aim The “2022 ACC/AHA Guideline for the Diagnosis and Management of Aortic
Disease” provides recommendations to guide clinicians in the diagnosis, genetic evaluation …

Aims Acute aortic dissection (AAD) is a life-threatening disease with high morbidity and
mortality. Previous studies have showed that vascular smooth muscle cell (VSMC) …

Background: To evaluate the diagnostic accuracy and clinical utility of the acute aortic
dissection detection risk score (ADD-RS) alone or with D-dimer as a screening test to …

Objective For intramural hematoma and penetrating atherosclerotic ulcer, long-term
behavior and treatment are controversial. This study evaluates the long-term behavior of …