Organoids are 3D cell culture systems derived from human pluripotent stem cells that
contain tissue resident cell types and reflect features of early tissue organization. Neural …

The derivation of induced pluripotent stem cells (iPSCs) over a decade ago sparked
widespread enthusiasm for the development of new models of human disease, enhanced …

Cells undergo a major epigenome reconfiguration when reprogrammed to human induced
pluripotent stem cells (hiPS cells). However, the epigenomes of hiPS cells and human …

Cellular agriculture is an emerging scientific discipline that leverages the existing principles
behind stem cell biology, tissue engineering, and animal sciences to create agricultural …

Induced pluripotent stem cell (iPSC) technologies have provided in vitro models of
inaccessible human cell types, yielding new insights into disease mechanisms especially for …

Using induced pluripotent stem cells (iPSCs) to understand the mechanisms of neurological
disease holds great promise; however, there is a lack of well-curated lines from a large array …

It is extremely rare for a single experiment to be so impactful and timely that it shapes and
forecasts the experiments of the next decade. Here, we review how two such experiments …

Technology utilizing human induced pluripotent stem cells (iPS cells) has enormous
potential to provide improved cellular models of human disease. However, variable genetic …

In vitro liver cell culture models are gaining increasing importance in pharmacological and
toxicological research. The source of cells used is critical for the relevance and the …

Variability in induced pluripotent stem cell (iPSC) lines remains a concern for disease
modeling and regenerative medicine. We have used RNA-sequencing analysis and linear …