The gut microbiota–brain axis in behaviour and brain disorders

LH Morais, HL Schreiber IV… - Nature Reviews …, 2021 - nature.com
In a striking display of trans-kingdom symbiosis, gut bacteria cooperate with their animal
hosts to regulate the development and function of the immune, metabolic and nervous …

Microbial-derived metabolites as a risk factor of age-related cognitive decline and dementia

E Connell, G Le Gall, MG Pontifex, S Sami… - Molecular …, 2022 - Springer
A consequence of our progressively ageing global population is the increasing prevalence
of worldwide age-related cognitive decline and dementia. In the absence of effective …

Clinical, gut microbial and neural effects of a probiotic add-on therapy in depressed patients: a randomized controlled trial

AC Schaub, E Schneider… - Translational …, 2022 - nature.com
A promising new treatment approach for major depressive disorder (MDD) targets the
microbiota-gut-brain (MGB) axis, which is linked to physiological and behavioral functions …

The microbiota-gut-brain axis

JF Cryan, KJ O'Riordan, CSM Cowan… - Physiological …, 2019 - journals.physiology.org
I. INTRODUCTION 1877 II. STUDYING THE... 1881 III. MICROBIOTA-GUT-BRAIN AXIS...
1907 IV. PATHWAYS OF COMMUNICATION 1911 V. MICROBIOTA AND SYNAPTIC... 1929 …

Bifidobacterium breve CCFM1025 attenuates major depression disorder via regulating gut microbiome and tryptophan metabolism: A randomized clinical trial

P Tian, Y Chen, H Zhu, L Wang, X Qian, R Zou… - Brain, behavior, and …, 2022 - Elsevier
Objective Psychobiotics, as a novel class of probiotics mainly acting on the gut-brain axis,
have shown promising prospects in treating psychiatric disorders. Bifidobacterium breve …

Diagnosis and treatment of irritable bowel syndrome: a review

M Camilleri - Jama, 2021 - jamanetwork.com
Importance The prevalence of irritable bowel syndrome (IBS) in the United States is between
7% and 16%, most common in women and young people, with annual direct costs estimated …

[HTML][HTML] Tryptophan metabolism: a link between the gut microbiota and brain

K Gao, C Mu, A Farzi, W Zhu - Advances in Nutrition, 2020 - Elsevier
The gut-brain axis (GBA) is a bilateral communication network between the gastrointestinal
(GI) tract and the central nervous system. The essential amino acid tryptophan contributes to …

An insight into gut microbiota and its functionalities

A Adak, MR Khan - Cellular and Molecular Life Sciences, 2019 - Springer
Gut microbiota has evolved along with their hosts and is an integral part of the human body.
Microbiota acquired at birth develops in parallel as the host develops and maintains its …

[HTML][HTML] The brain-gut-microbiome axis

CR Martin, V Osadchiy, A Kalani, EA Mayer - Cellular and molecular …, 2018 - Elsevier
Preclinical and clinical studies have shown bidirectional interactions within the brain-gut-
microbiome axis. Gut microbes communicate to the central nervous system through at least …

Systematic review of gut microbiota and major depression

SG Cheung, AR Goldenthal, AC Uhlemann… - Frontiers in …, 2019 - frontiersin.org
Background: Recently discovered relationships between the gastrointestinal microbiome
and the brain have implications for psychiatric disorders, including major depressive …