Sporotrichosis in immunocompromised hosts

F Queiroz-Telles, R Buccheri, G Benard - Journal of Fungi, 2019 - mdpi.com
Sporotrichosis is a global implantation or subcutaneous mycosis caused by several
members of the genus Sporothrix, a thermo-dimorphic fungus. This disease may also depict …

Role for IL-1 family cytokines in fungal infections

JS Griffiths, G Camilli, NK Kotowicz, J Ho… - Frontiers in …, 2021 - frontiersin.org
Fungal pathogens kill approximately 1.5 million individuals per year and represent a severe
disease burden worldwide. It is estimated over 150 million people have serious fungal …

The NLRP3 inflammasome contributes to host protection during Sporothrix schenckii infection

AC Gonçalves, LS Ferreira, FA Manente… - …, 2017 - Wiley Online Library
Sporotrichosis is a mycosis caused by fungi from the Sporothrix schenckii species complex,
whose prototypical member is Sporothrix schenckii sensu stricto. Pattern recognition …

The Role of Macrophages in the Host's Defense against Sporothrix schenckii

E Ruiz-Baca, A Pérez-Torres, Y Romo-Lozano… - Pathogens, 2021 - mdpi.com
The role of immune cells associated with sporotrichosis caused by Sporothrix schenckii is
not yet fully clarified. Macrophages through pattern recognition receptors (PRRs) can …

Immunopathogenesis of human sporotrichosis: what we already know

F Conceição-Silva, FN Morgado - Journal of fungi, 2018 - mdpi.com
Sporotrichosis is a subacute/chronic mycosis caused by dimorphic fungus of the genus
Sporothrix. This mycosis may affect both human and domestic animals and in the last few …

Inflammasomes and dermatology

DC Sá, C Festa - Anais brasileiros de dermatologia, 2016 - SciELO Brasil
Inflammasomes are intracellular multiprotein complexes that comprise part of the innate
immune response. Since their definition, inflammasome disorders have been linked to an …

A cell wall protein-based vaccine candidate induce protective immune response against Sporothrix schenckii infection

DL Portuondo, A Batista-Duharte, LS Ferreira… - Immunobiology, 2016 - Elsevier
Sporotrichosis is a subcutaneous mycosis caused by several closely related thermo-
dimorphic fungi of the Sporothrix schenckii species complex, affecting humans and other …

Sporothrix brasiliensis induces a more severe disease associated with sustained Th17 and regulatory T cells responses than Sporothrix schenckii sensu stricto in …

A Batista-Duharte, D Téllez-Martínez, CR de Andrade… - Fungal biology, 2018 - Elsevier
Little is known about the differences in the CD4+ T-cell response induced by Sporothrix
schenckii and Sporothrix brasiliensis, the most virulent species that cause sporotrichosis …

Optimal clearance of Sporothrix schenckii requires an intact Th17 response in a mouse model of systemic infection

LS Ferreira, AC Goncalves, DL Portuondo, DCG Maia… - Immunobiology, 2015 - Elsevier
The discovery of Th17 cells, along with many other Th cell subsets in the recent years, has
expanded the Th1/Th2 paradigm that had persisted since its proposition by Mosmann in …

Comparative efficacy and toxicity of two vaccine candidates against Sporothrix schenckii using either Montanide™ Pet Gel A or aluminum hydroxide adjuvants in mice

DL Portuondo, A Batista-Duharte, LS Ferreira… - Vaccine, 2017 - Elsevier
Sporotrichosis is an important zoonosis in Brazil and the most frequent subcutaneous
mycosis in Latin America, caused by different Sporothrix species. Currently, there is no …