Helminth parasites infect almost one-third of the world's population, primarily in tropical
regions. However, regions where helminth parasites are endemic record much lower …

Immunology was founded by studying the body's response to infectious microorganisms,
and yet microbial prokaryotes only tell half the story of the immune system. Eukaryotic …

Adeno-associated viruses (AAVs) are small, nonenveloped single-stranded DNA viruses
that require helper viruses to facilitate efficient replication. Despite the presence of humoral …

Exposure to infective larvae of the filarial nematode Onchocerca volvulus (Ov) either results
in patent infection (microfilaridermia) or it leads to a status called putative immunity …

Toxocara canis has extraordinary abilities to survive for many years in the tissues of diverse
vertebrate species, as well as to develop to maturity in the intestinal tract of its definitive …

The secretome of a parasite in its definitive host can be considered to be its genome in trans,
to the extent that secreted products encoded by the parasite fulfill their function in the host …

The identification of crossregulating T helper (Th) cells has revolutionized current
understanding of the immune response to infection. While paying tribute to this revolution …

Among the causes of lymphoedema (LE), secondary LE due to filariasis is the most
prevalent. It affects only a minority of the 120 million people infected with the causative …

Filarial nematode parasites establish long-term chronic infections in the context of an
antiparasite immunity that is strongly biased toward a Th2 response. The mechanisms that …

Phosphorylcholine (PC) is a structural component of a variety of prokaryotic and eukaryotic
pathogens. In some cases, PC in infectious agents can benefit the infected host due to its …