Over the last century, the tremendous growth in industrial activities particularly in the sectors
of pharmaceuticals, petrochemicals and the reckless application of fertilizers and …

The construct of frailty was first developed in gerontology to help identify older adults with
increased vulnerability when confronted with a health stressor. This article is a review of …

Acute kidney disease (AKD)-which includes acute kidney injury (AKI)–and chronic kidney
disease (CKD) are highly prevalent among hospitalized patients, including those in …

There are only 2 treatments for the thousands of patients who progress to the most
advanced form of heart failure despite the application of guideline-based medical therapy …

Background. Frailty is a multidimensional condition and is the result of the body's age-
associated decline in physical, cognitive, physiological, and immune reserves. The aim of …

Background & Aims Old age must be considered in weighing the risks of complications vs
benefits of treatment for patients with inflammatory bowel diseases (IBD). We conducted a …

Background There is currently no consensus as to a standardized tool for frailty
measurement in any patient population. In the solid-organ transplantation population …

Conclusions Unchaperoned iron in PCBP1‐deleted mouse hepatocytes leads to production
of ROS, resulting in lipid peroxidation (LPO) and steatosis in the absence of iron overload …

The population is aging. Although older adults have higher rates of comorbidities and
adverse health events, they represent a heterogeneous group with different health …

BACKGROUND Frailty is prevalent in the patients with advanced heart failure; however, its
impact on clinical outcomes after heart transplantation (HTx) is unclear. The aim of this study …