Lipid droplets and polyunsaturated fatty acid trafficking: Balancing life and death

M Danielli, L Perne, E Jarc Jovičić… - Frontiers in Cell and …, 2023 - frontiersin.org
Lipid droplets are fat storage organelles ubiquitously distributed across the eukaryotic
kingdom. They have a central role in regulating lipid metabolism and undergo a dynamic …

Uncoupling protein 1 does not produce heat without activation

Y Li, T Fromme - International Journal of Molecular Sciences, 2022 - mdpi.com
Mitochondrial uncoupling protein 1 (UCP1) is the crucial mechanistic component of heat
production in classical brown fat and the newly identified beige or brite fat. Thermogenesis …

[HTML][HTML] Loss of UCP1 function augments recruitment of futile lipid cycling for thermogenesis in murine brown fat

J Oeckl, P Janovska, K Adamcova, K Bardova… - Molecular …, 2022 - Elsevier
Objective Classical ATP-independent non-shivering thermogenesis enabled by uncoupling
protein 1 (UCP1) in brown adipose tissue (BAT) is activated, but not essential for survival, in …

Abnormal lipid metabolism in cancer-associated cachexia and potential therapy strategy

R Fang, L Yan, Z Liao - Frontiers in Oncology, 2023 - frontiersin.org
Cancer-associated cachexia (CAC) is a major characteristic of advanced cancer, associates
with almost all types of cancer. Recent studies have found that lipopenia is an important …

Association between “cluster of differentiation 36 (CD36)” and adipose tissue lipolysis during exercise training: A systematic review

EM El Ouali, L Bosquet, B Elgharbaoui, F Laziri… - Frontiers in …, 2023 - frontiersin.org
Fatty acid translocase (FAT/CD36) is a transmembrane glycoprotein belonging to the
scavenger class B receptor family and is encoded by the cluster of differentiation 36 (CD36) …

Advancements in the alcohol-associated liver disease model

L Zhu, HD Li, JJ Xu, JJ Li, M Cheng, XM Meng… - Biomolecules, 2022 - mdpi.com
Alcohol-associated liver disease (ALD) is an intricate disease that results in a broad
spectrum of liver damage. The presentation of ALD can include simple steatosis …

Sex hormone-binding globulin improves lipid metabolism and reduces inflammation in subcutaneous adipose tissue of metabolic syndrome-affected horses

L Bourebaba, M Kępska, B Qasem, M Zyzak… - Frontiers in molecular …, 2023 - frontiersin.org
Equine metabolic syndrome (EMS) is a steadily growing endocrine disorder representing a
real challenge in veterinary practice. As a multifactorial condition, EMS is characterized by …

Is insulin resistance tissue-dependent and substrate-specific? The role of white adipose tissue and skeletal muscle

D Calderón-DuPont, I Torre-Villalvazo… - Biochimie, 2023 - Elsevier
Insulin resistance (IR) refers to a reduction in the ability of insulin to exert its metabolic
effects in organs such as adipose tissue (AT) and skeletal muscle (SM), leading to chronic …

Essential Oil of Carvone Chemotype Lippia alba (Verbenaceae) Regulates Lipid Mobilization and Adipogenesis in Adipocytes

K Bonilla-Carvajal, EE Stashenko… - Current Issues in …, 2022 - mdpi.com
Obesity is characterized by an expansion of adipose tissue due to excessive accumulation
of triglycerides in adipocytes, causing hypertrophy and hyperplasia, followed by hypoxia …

Black wheat extracts (arriheuk) regulate adipogenesis and lipolysis via adenosine monophosphate (AMP) activated protein kinase (AMPK)/sirtuin 1 (SIRT1) signaling …

Y Yoon, MK Park, KH Kim, GH Lee - Foods, 2023 - mdpi.com
Polyphenols and other compounds with antioxidant properties are found in plants and are
one of the main antioxidants proven to reduce body weight and the risk of insulin resistance …