Medical physics challenges in clinical MR-guided radiotherapy

C Kurz, G Buizza, G Landry, F Kamp, M Rabe… - Radiation …, 2020 - Springer
The integration of magnetic resonance imaging (MRI) for guidance in external beam
radiotherapy has faced significant research and development efforts in recent years. The …

MRI-guidance for motion management in external beam radiotherapy: current status and future challenges

C Paganelli, B Whelan, M Peroni… - Physics in Medicine …, 2018 - iopscience.iop.org
High precision conformal radiotherapy requires sophisticated imaging techniques to aid in
target localisation for planning and treatment, particularly when organ motion due to …

Radiotherapy planning using MRI

MA Schmidt, GS Payne - Physics in Medicine & Biology, 2015 - iopscience.iop.org
The use of magnetic resonance imaging (MRI) in radiotherapy (RT) planning is rapidly
expanding. We review the wide range of image contrast mechanisms available to MRI and …

Comprehensive MRI simulation methodology using a dedicated MRI scanner in radiation oncology for external beam radiation treatment planning

ES Paulson, B Erickson, C Schultz, X Allen Li - Medical physics, 2015 - Wiley Online Library
Purpose: The use of magnetic resonance imaging (MRI) in radiation oncology is expanding
rapidly, and more clinics are integrating MRI into their radiation therapy workflows. However …

4D respiratory motion‐compensated image reconstruction of free‐breathing radial MR data with very high undersampling

CM Rank, T Heußer, MTA Buzan… - Magnetic resonance …, 2017 - Wiley Online Library
Purpose To develop four‐dimensional (4D) respiratory time‐resolved MRI based on free‐
breathing acquisition of radial MR data with very high undersampling. Methods We propose …

Motion prediction in MRI-guided radiotherapy based on interleaved orthogonal cine-MRI

M Seregni, C Paganelli, D Lee, PB Greer… - Physics in Medicine …, 2016 - iopscience.iop.org
In-room cine-MRI guidance can provide non-invasive target localization during radiotherapy
treatment. However, in order to cope with finite imaging frequency and system latencies …

Intensity‐modulated proton therapy (IMPT) interplay effect evaluation of asymmetric breathing with simultaneous uncertainty considerations in patients with non‐small …

J Shan, Y Yang, SE Schild, TB Daniels… - Medical …, 2020 - Wiley Online Library
Purpose Intensity‐modulated proton therapy (IMPT) is sensitive to uncertainties from patient
setup and proton beam range, as well as interplay effect. In addition, respiratory motion may …

Feasibility study on 3D image reconstruction from 2D orthogonal cine‐MRI for MRI‐guided radiotherapy

C Paganelli, D Lee, J Kipritidis… - Journal of medical …, 2018 - Wiley Online Library
Introduction In‐room MRI is a promising image guidance strategy in external beam
radiotherapy to acquire volumetric information for moving targets. However, limitations in …

Real-time 2D-3D deformable registration with deep learning and application to lung radiotherapy targeting

MD Foote, BE Zimmerman, A Sawant… - Information Processing in …, 2019 - Springer
Radiation therapy presents a need for dynamic tracking of a target tumor volume. Fiducial
markers such as implanted gold seeds have been used to gate radiation delivery but the …

Real-time MRI motion estimation through an unsupervised k-space-driven deformable registration network (KS-RegNet)

HC Shao, T Li, MJ Dohopolski, J Wang… - Physics in Medicine …, 2022 - iopscience.iop.org
Purpose. Real-time three-dimensional (3D) magnetic resonance (MR) imaging is
challenging because of slow MR signal acquisition, leading to highly under-sampled k …