Virtually all organosulfur compounds react with Fe (0) carbonyls to give the title complexes.
These reactions are reviewed in light of major advances over the past few decades, spurred …

Conspectus The seeds for recognition of the vast superfamily of radical S-adenosyl-l-
methionine (SAM) enzymes were sown in the 1960s, when Joachim Knappe found that the …

Nature uses multinuclear metal clusters to catalyse a number of important multielectron
redox reactions. Examples that employ complex Fe–S clusters in catalysis include the Fe …

[FeFe] hydrogenases carry out the redox interconversion of protons and molecular hydrogen
(2H++ 2e−⇌ H2) at a complex Fe–S active site known as the H-cluster. The H-cluster …

[FeFe] hydrogenases contain a 6-Fe cofactor that serves as the active site for efficient redox
interconversion between H2 and protons. The biosynthesis of the so-called H-cluster …

Conspectus Nature's prototypical hydrogen-forming catalysts─ hydrogenases─ have
attracted much attention because they catalyze hydrogen evolution at near zero …

[FeFe] hydrogenases are enzymes capable of producing and oxidizing H2 at staggering
submillisecond time scales. A major limitation in applying these enzymes for industrial …

Here we describe maturation of the [FeFe]-hydrogenase from its [4Fe–4S]-bound precursor
state by using the synthetic complex [Fe2 (μ-SH) 2 (CN) 2 (CO) 4] 2− together with HydF and …

Peptide-derived natural products are a class of metabolites that afford the producing
organism a selective advantage over other organisms in their biological niche. While the …

Radical SAM (RS) enzymes use S-adenosyl-l-methionine (SAM) and a [4Fe–4S] cluster to
initiate a broad spectrum of radical transformations throughout all kingdoms of life. We report …